Results 281 to 290 of about 19,205,329 (382)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma. [PDF]

Clin Transl Med
Xi X, Ding X, Wang Q, Liu N, Wang B, Wang G, Zhong W, Lu Y.   +7 more
europepmc   +1 more source

PS1454 CAG PROMOTER DRIVEN C‐MYC OVEREXPRESSION CAUSES RAPIDLY LETHAL CARDIOMYOPATHY

, 2019
Sarolta Bojtine Kovacs, Trinanjan Basu, HL Pahl   +2 more
openalex   +1 more source

LncRNA‐MIF, a c‐Myc‐activated long non‐coding RNA, suppresses glycolysis by promoting Fbxw7‐mediated c‐Myc degradation

EMBO Reports, 2016
Pengfei Zhang, Limian Cao, Pingsheng Fan, Yide Mei, Mian Wu   +4 more
semanticscholar   +1 more source

c-Myc-abhängige Regulation des Zellzyklusinhibitors p27Kip1 [PDF]

, 2001
Prof. Dr. M. A. Marahiel, Thieke, Katja
core   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

GAB2 regulates lipid metabolism by activating the MEK/ERK/c-Myc pathway: impact on renal cell carcinoma progression. [PDF]

Eur J Med Res
Zhang W, Fei X, Qin P, Sun Y, Zhu Z, Huang N, Li X, Li Z, Liu T.   +8 more
europepmc   +1 more source

c-MYC Expression is Modulated by Statins Use and it's Correlated with Time to Progression (TTP) in Men with Localised Prostate Cancer Treated with Radical Radiotherapy

, 2012
D. Torrejon Castro, Inés de Torres, Gessamí Sánchez-Ollé, Xavier Maldonado, Rafael Morales‐Barrera, Cristina Suárez, C. Valverde Morales, I. Nunez Hernandez, Juan Moróte, Joan Carles   +9 more
openalex   +1 more source

HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc.

Cancer Research, 2016
Yinghui Li, Zhen Wang, Hui Shi, Hang Li, Leilei Li, Runping Fang, Xiao-li Cai, Bo-wen Liu, Xiao-dong Zhang, L. Ye   +9 more
semanticscholar   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source