Results 101 to 110 of about 321,288 (261)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Development of a C-RAN Fronthaul Simulator

open access: yes, 2023
Mobilnäten har förändrat hur vi kommunicerar och får tillgång till data, och datahastigheterna har bara ökat under de senaste 30 åren. 5G är den nuvarande generationen av mobilnät och möjliggör snabbare datahastigheter och lägre latens. En av de mobilnät arkitekturer som används för att möjliggöra 5g är centraliserade radioaccessnät (C-RAN).
Tesfalidet, Noel, Khosravi, Sam
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Cloud Radio Random-Access Networks With Multi-Packet Reception Capability

open access: yesIEEE Access
Cloud Radio Access Network (C-RAN) refers to the virtualization of base station functionalities by means of cloud computing. With centralized processing at the cloud, the amount of hardware and infrastructure in a network can be reduced and it allows for
Cheolkyu Shin   +3 more
doaj   +1 more source

Rateless Coded Uplink Transmission Design for Multi-User C-RAN. [PDF]

open access: yesSensors (Basel), 2019
Zhang Y, Xu J, Peng H, Lu W, Zhang Z.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

C-RAN in realistic scenarios

open access: yes, 2019
In the first part is described the LTE system containing a description of all the aspects and parameters that should be taken into account when planning. Then there is a Software Planning Tool named Mentum Planet guidelines with detailed and ordered description of all the steps that someone should do to reproduce the LTE planning, with explanations ...
openaire   +1 more source

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