Results 81 to 90 of about 321,288 (261)

Federated Learning-Driven IoT Request Scheduling for Fault Tolerance in Cloud Data Centers

open access: yesMathematics
Cloud computing is a virtualized and distributed computing model that provides resources and services based on demand and self-service. Resource failure is one of the major challenges in cloud computing, and there is a need for fault tolerance mechanisms.
Sheeja Rani S, Raafat Aburukba
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Power-Efficient Resource Allocation in Massive MIMO Aided Cloud RANs

open access: yesInternational Journal of Information and Communication Technology Research, 2018
This paper considers the power-efficient resource allocation problem in a cloud radio access network (C-RAN). The C-RAN architecture consists of a set of base-band units (BBUs) which are connected to a set of radio remote heads (RRHs) equipped with ...
Nahid Amani   +3 more
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Not just phonology: a longitudinal study of dyslexia subtypes based on the distinction between reading accuracy and reading rate

open access: yesFrontiers in Language Sciences
IntroductionPrevious cross-sectional investigations by Shany and colleagues have provided evidence of double dissociation among dyslexics between word reading accuracy and (pure) word reading rate.
Maysa Jabbour-Danial   +2 more
doaj   +1 more source

Adaptive Transceiver Design for C-RAN in mmWave Communications

open access: yesIEEE Access, 2018
An adaptive array design is proposed for hybrid beamforming in millimeter-wave (mmWave) communications in the context of cloud radio access networks (C-RAN). More explicitly, the adaptive design focuses on the physical layer aspect of C-RAN.
K. Satyanarayana   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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