Results 91 to 100 of about 20,153,654 (297)

Positioning via direct localisation in C‐RAN systems

IET Communications, 2016
Cloud radio access network (C‐RAN) is a prominent architecture for fifth generation wireless cellular system that is based on the centralisation of baseband processing for multiple distributed radio units (RUs) at a control unit (CU). In this study, it is proposed to leverage the C‐RAN architecture to enable the implementation of
Seongah Jeong, Osvaldo Simeone, Alexander M. Haimovich, Joonhyuk Kang   +3 more
openaire   +4 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Distributed Location Algorithms for Flexible BBU Hotel Placement in C-RAN

, 2018
Cloud Radio Access Networks (C-RAN) are characterized by huge introduction of Network Function Virtualization (NFV) supported by software-based control of relevant functionalities within the Soft- ware Dened Network (SDN) context.
Bahare Masood Khorsandi, Carla Raffaelli, Federico Tonini   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

FA-CRAN: A Firefly Algorithm for Dynamic BBU-RRH Mapping in Cloud/Centralized Radio Access Networks

IEEE Access
C-RAN (Cloud Radio Access Network) is an architecture designed to the new generation of mobile networks. It has handled many problems arising from the 4-generation network, and made several improvements, such as centralized processing and energy ...
Mariane de Paula da Silva Goncalves Imbiriba, Erminio Augusto Ramos da Paixao, Albert Einstein Coutinho Dos Santos, Carlos Andre de Mattos Teixeira, Rafael Fogarolli Vieira, Daniel da Silva Souza, Igor Wenner Silva Falcao, Diego Lisboa Cardoso   +7 more
doaj   +1 more source

Evaluation of Packet Preemption over C-RAN Fronthaul Networks [PDF]

, 2017
The Cloud Radio Access Network (C-RAN) is viewed as a new solution with benefits of reduced cost by sharing resources. This is achieved by the separation of the radio part and the radio processing part, where the transport network between them is ...
Berger, Michael Stübert, Zhou, Zifan, Ruepp, Sarah Renée, Yan, Ying   +3 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Solution structure of the Ran-binding domain 2 of RanBP2 and its interaction with the C terminus of Ran

, 2005
The termination of export processes from the nucleus to the cytoplasm in higher eukaryotes is mediated by binding of the small GTPase Ran as part of the export complexes to the Ran-binding domains (RanBD) of Ran-binding protein 2 (RanBP2) of the nuclear ...
Kuhlmann, J., Kalbitzer, Hans-Robert, Geyer, J. Peter, Kremer, W., Döker, R., Zhao, X., Zhao, Xiaodong, Kremer, Werner, Geyer, J., Döker, Rolf, Kalbitzer, H., Kuhlmann, Jürgen   +11 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source