Results 71 to 80 of about 20,153,654 (297)

GEF-independent Ran activation shifts a fraction of the protein to the cytoplasm and promotes cell proliferation

Molecular Biomedicine, 2020
Ran (Ras-related nuclear protein) plays several important roles in nucleo-cytoplasmic transport, mitotic spindle formation, nuclear envelope/nuclear pore complex assembly, and other functions in the cytoplasm, as well as in cellular transformation when ...
Jinhan Zhou, Yuping Tan, Yuqing Zhang, Aiping Tong, Xiaofei Shen, Xiaodong Sun, Da Jia, Qingxiang Sun   +7 more
doaj   +1 more source

Cost-effective resource allocation in C-RAN with mobile cloud

, 2016
Taking full advantages of two cloud-based techniques, i.e., cloud radio access network (C-RAN) and mobile cloud computing (MCC), mobile operators will be able to provide the good service to the mobile user as well as increasing their revenue.
Wang, Kezhi, Kezhi Wang, Wang, Xinhou, Yang, Kun, Xinhou Wang, Chathura Sarathchandra Magurawalage, Yang, Kunder D, Magurawalage, Chathura, S, Magurawalage, Chathura Sarathchandra, Kun Yang   +9 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Parallel Interference Cancellation for Cell-Free C-RANs

2020 54th Asilomar Conference on Signals, Systems, and Computers, 2020
This paper formulates a linear receiver for the uplink of centralized, possibly cloud-based, radio access networks operating in a cell-free fashion. This receiver, which draws on the notion of soft parallel interference cancellation, exhibits substantial interference rejection abilities, yet it does not involve any matrix inversions.
Mosayebi, Reza, Mojahedian, Mohammad M., Lozano, Angel   +2 more
openaire   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

How to Migrate from Operational LTE/LTE–A Networks to C–RAN with Minimal Investment

, 2018
By leveraging the fully–centralized and virtualized Cloud Radio Access Network (C–RAN) architecture over densely deployed small cells, Mobile Network Operators (MNOs) are expected to meet the ever–increasing coverage and capacity demands.
Roberto Riggio, Davit Harutyunyan
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

End-to-End Energy Efficiency Evaluation of 5G Networks in Dense Urban and Rural Scenarios Using Empirical Modeling and Monte Carlo Simulation

Applied Sciences
This paper provides a comprehensive end-to-end evaluation of the energy efficiency of three key fifth-generation mobile (5G) Radio Access Network (RAN) architectures: Distributed RAN (D-RAN), Centralized RAN (C-RAN), and Cloud C-RAN.
Bhuvaneshwar Doorgakant, Tulsi Pawan Fowdur, Mobayode O. Akinsolu   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source