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Mendelian randomization analysis: The causal relationship between C-reactive protein and amyloidosis and between C-reactive protein and atherosclerosis. [PDF]

PLoS ONE
BackgroundA number of studies have shown that elevated CRP is linked to AS and reduced CRP is linked to amyloidosis. However, the exact mechanism explaining this connection is not known.MethodsWe used genomic pooled data from the Genome-Wide Association ...
Chunhui Liu, Xupeng Huang, Yongsheng Huang, Hongguang Jin   +3 more
doaj   +2 more sources

C-reactive Protein [PDF]

Journal of Biological Chemistry, 2004
C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologs in vertebrates and many invertebrates, that participates in the systemic response to inflammation. Its plasma concentration increases during inflammatory states, a characteristic that has long been employed for clinical purposes.
Steven, Black, Irving, Kushner, David, Samols   +2 more
  +7 more sources

C-Reactive Protein [PDF]

Circulation, 2001
In the present issue, Chew and colleagues 1 show that elevated baseline C-reactive protein (CRP) levels before percutaneous coronary intervention (PCI) are associated with a progressive increase in the risk of death or myocardial infarction at 30 days. The independent association of risk attributable to the marker CRP remained, even after adjusting for
Edward T.H. Yeh, H.Vernon Anderson, Vincenzo Pasceri, James T. Willerson   +3 more
  +4 more sources

Dependence of C-Reactive Protein & Cholesterol [PDF]

Kirkuk Journal of Science, 2011
This study had been designed to illustrate the relationship between immunological and biochemical abnormalities in patients with coronary heart disease (CHD) in Dohuk. These patients were referred to the general Azadi hospital in Dohuk for investigation.
Malika K. Najeeb Al Barwari, Ahmed S. Mirza Al- Barwari   +1 more
doaj   +1 more source

Therapeutic Lowering of C-Reactive Protein

Frontiers in Immunology, 2021
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectious ...
Rachel V. Jimenez, Alexander J. Szalai
doaj   +1 more source

Deficiency of C-reactive protein or human C-reactive protein transgenic treatment aggravates influenza A infection in mice

Frontiers in Immunology, 2022
C-reactive protein (CRP) has been shown to be a potential candidate target in the immunotherapy of severe influenza A infection. However, it is unclear on the pathogenesis associated with CRP in influenza infections.
Zhuohan Zhang, Zhuohan Zhang, Yongjun Gao, Yongjun Gao, Li Li, Li Li, Junhao Luo, Junhao Luo, Rongbao Gao, Rongbao Gao   +9 more
doaj   +1 more source

C-REACTIVE PROTEIN

Journal of Akhtar Saeed Medical & Dental College, 2023
C-reactive protein (CRP) is synthesized in the liver after macrophages and T-lymphocytes secrete interleukins.It is an acute phase protein,and the normal concentration ranges from0.8 mg/L to 3 mg/L. It is used as a markerof inflammation.
Naila Hamid, Muhammad Sohail Aslam
openaire   +1 more source

Role of C-Reactive Protein at Sites of Inflammation and Infection

Frontiers in Immunology, 2018
C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, Jason J. Ashworth
doaj   +1 more source

C-Reactive Protein in Atherothrombosis and Angiogenesis

Frontiers in Immunology, 2018
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation, or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions.
Lina Badimon, Lina Badimon, Esther Peña, Esther Peña, Gemma Arderiu, Teresa Padró, Teresa Padró, Mark Slevin, Gemma Vilahur, Gemma Vilahur, Gemma Chiva-Blanch   +10 more
doaj   +1 more source

Evolution of C-Reactive Protein

Frontiers in Immunology, 2019
C-reactive protein (CRP) is an evolutionarily conserved protein. From arthropods to humans, CRP has been found in every organism where the presence of CRP has been sought.
Asmita Pathak, Alok Agrawal
doaj   +1 more source