Results 171 to 180 of about 78,879 (258)

The C-reactive Protein-Triglyceride-Glucose Index in Relation to Liver Disease. [PDF]

Inquiry
Fang J, Liu L.
europepmc   +1 more source

Nonlinear association of triglyceride‐glucose body mass index with all‐cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The triglyceride‐glucose body mass index (TyG‐BMI) is a novel indicator combining an insulin resistance proxy (TyG index) with adiposity. It remains unclear how TyG‐BMI relates to long‐term mortality risk in postmenopausal women, a group prone to metabolic changes after menopause.
Xiliang Wang, Kaiyue Wang, Chang Tan, Yuexin Yu   +3 more
wiley   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Association of C-reactive protein-triglyceride-glucose index with all-cause and cardiovascular mortality in postmenopausal women. [PDF]

Prz Menopauzalny
Wang J, Li A, Wang Y, Liu Y.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

The association of C-reactive protein-triglyceride-glucose index with cardiometabolic multimorbidity in middle-aged and older adults: evidence from two cohort studies. [PDF]

Cardiovasc Diabetol
Lin Y, Tao J, Wang H, Guan H, Liu X, Dong X, Gao W.   +6 more
europepmc   +1 more source

Performance of different nutrition risk screening tools in predicting malnutrition in critically ill children on mechanical ventilation: A comparison study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This study aimed to characterize the distribution of nutrition status and nutrition risk stratification in critically ill children undergoing mechanical ventilation and to evaluate the association of nutrition risk with their clinical outcomes.
Ning Li, Jing Chen, Xiuxiu Lu, Wei Li, Dong Qu, Shuang Liu, Lin Wang   +6 more
wiley   +1 more source

Design characteristics of studies evaluating the effect of non‐surgical periodontal treatment on systemic health outcomes

Journal of Periodontology, EarlyView.
Abstract Background Evidence for whether and how non‐surgical periodontal treatment (NSPT) improves systemic outcomes remains equivocal. Inconclusive findings may in part be due to design variations of randomized controlled trials (RCTs) in this field.
Timothy Treat, Dylan Jones, Natalie Lorenzano, Scott Umberfield, Andrew Bartels, Titus Schleyer, Heather Taylor   +6 more
wiley   +1 more source