Results 51 to 60 of about 78,879 (253)

Black Beans, Fiber, and Antioxidant Capacity Pilot Study: Examination of Whole Foods vs. Functional Components on Postprandial Metabolic, Oxidative Stress, and Inflammation in Adults with Metabolic Syndrome. [PDF]

, 2015
Beans (Phaseolus vulgaris) contain bioactive components with functional properties that may modify cardiovascular risk. The aims of this pilot study were to evaluate the ability of black beans to attenuate postprandial metabolic, oxidative stress, and ...
Burton-Freeman, Britt M, Edirisinghe, Indika, Kappagoda, C Tissa, Randolph, Jody M, Reverri, Elizabeth J, Steinberg, Francene M   +5 more
core   +3 more sources

Exploring metabolic dysfunction in chronic kidney disease [PDF]

, 2012
Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core   +2 more sources

Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]

, 2017
The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio, Donini, Lorenzo Maria, Lenzi, Andrea, Pacifico, Lucia, Poggiogalle, Eleonora   +4 more
core   +2 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Triglyceride-glucose (TyG) index combined with C-reactive protein outperforms the TyG index alone in predicting stroke in arthritis patients: a nationwide prospective cohort study

Lipids in Health and Disease
Background Arthritis patients exhibit a higher stroke risk, but effective predictive biomarkers are scarce. This research sought to examine and compare the associations between the triglyceride-glucose (TyG) index, its integration with C-reactive protein
Zhongwei Zhou, Jianshu Gao, Mingzhong Sun, Hongmei Chen, Hao Jin, Huixiang Ju   +5 more
doaj   +1 more source

The comprehensive effects of high-sensitivity C-reactive protein and triglyceride glucose index on cardiometabolic multimorbidity

Frontiers in Endocrinology
BackgroundThe triglyceride-glucose index (TyG index) is one of the surrogate markers of insulin resistance, and high-sensitivity C-reactive protein (hsCRP) reflects systemic inflammation.
Bingen Wan, Silin Wang, Sheng Hu, Weiqing Han, Shengyu Qiu, Lingxiao Zhu, Liancheng Ruan, Yiping Wei, Jianjun Xu   +8 more
doaj   +1 more source

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration [PDF]

, 2011
AIMS: To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association
Angelakopoulou, A, Berry, DJ, Casas, JP, Caulfield, M, Cooper, J, de Faire, U, Deanfield, J, Drenos, F, Fowkes, FG, Gigante, B, Hardy, R, Hingorani, AD, Humphries, SE, Hypponen, E, Ireland, H, Jefferis, BJ, Kivimaki, M, Kuh, D, Kumari, M, Lathrop, M, Laxton, RC, Leander, K, Maniatis, N, Marmot, M, Morris, RW, Motterle, A, Munroe, PB, Palmen, J, Power, C, Price, J, Samani, N, Shah, S, Shah, T, Simpson, IA, Smeeth, L, Sofat, R, Talmud, PJ, Thomson, A, Tzoulaki, I, Verzilli, C, Wallace, C, Whincup, PH, Whittaker, JC, Wong, A, Ye, S   +44 more
core   +4 more sources

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

A Novel Index Using Soluble CD36 Is Associated with the Prevalence of Type 2 Diabetes Mellitus: Comparison Study with Triglyceride-Glucose Index [PDF]

Endocrinology and Metabolism, 2017
BackgroundPlasma soluble cluster determinant 36 (sCD36) level is closely related with insulin resistance and atherosclerosis, but little is known whether it could be a surrogate for estimating risk of developing diabetes or not.
Ho Jin Kim, Jun Sung Moon, Il Rae Park, Joong Hee Kim, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee   +6 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source