Results 91 to 100 of about 1,151,537 (267)
Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more sourceAssessment of C-reactive protein and procalcitonin levels to predict infection and mortality in burn children
, 2014 Juan P. Garrahan, María Teresa Rosanova, Nidia Tramonti, Moira Taicz, Soledad Martiren, Hugo Basílico, Cecilia Signorelli, Ana Buchovsky, Roberto Lede, Pruitt Ba, A Mcmanus, M Rosanova, D Stamboulian, R Lede, C Mayhall, M Rosanova, D Stamboulian, R Lede, M Barati, F Alinejad, M Bahar, M Tabrisi, P Povoa, D Greenhalgh, J Saffle, J Holmes, R Gamelli, M Geyik, M Aldemir, S Hosoglu, H Tacyildiz, M Heideman, A Bengstsson, R Sheridan, C Murray, R Hoffmaster, D Schmit, D Hospenthal, Von Heimburg, D Stieghorst, W Khorram-Sefat, R Pallua, N, S Lobo, F Lobo, D Bota, F Lopes-Ferreira, Burn Belgianoutcome In, Study Injury, Group, T Housinger, C Brinkerhoff, G Warden, D Jaye, K Waites, M Jeschke, C Finnerty, G Kulp, R Kraft, A Neely, L Fowler, R Kagan, G Warden, G Castelli, C Pognani, M Meisner, A Stuani, L Seoane, S Pertega, R Galeiras, I Astola, E Mann, G Wood, C Wade, H Kim, H Yang, J Hur, W Chun, A Lavrentieva, S Papadopoulou, J Kioumis, E Kaimakamis +81 moreopenalex +1 more sourcePotential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk +4 morewiley +1 more sourceExploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair +17 morewiley +1 more sourceValue of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease
International Journal of COPD, 2011 Alicia Lacoma1,4, Cristina Prat1,4, Felipe Andreo2,4, Luis Lores3, Juan Ruiz-Manzano2,4, Vicente Ausina1,4, Jose Domínguez1,41Servei de Microbiologia, 2Servei de Pneumologia, Hospital Universitari Germans Trias i Pujol, Fundació ...Alicia Lacoma, Cristina Prat, Felipe Andreo, et al +3 moredoaj Predictive Value of Some Inflammatory Indexes in the Survival and Toxicity of Nasopharyngeal Carcinoma
Cancer Management and Research, 2020 Yu-Yuan Han,1,2 Kai-Hua Chen,1,2 Ying Guan,1 Li Chen,1,2 Man-Ru Lin,1 Si-Kai Nong,3 Xiao-Dong Zhu1– 3 1Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi 530021, People’s Republic of China; 2Guangxi Han YY, Chen KH, Guan Y, Chen L, Lin MR, Nong SK, Zhu XD +6 moredoaj High Sensitivity C Reactive Protein (hs-CRP) in Adolescent and Young Adult Patients with History of Kawasaki Disease.
, 2015 Yung Chuan Chen, Ching Shen, Nan Koong Wang, Yi Huang, Hsin‐Hui Chiu, Chun‐An Chen, Shuenn‐Nan Chiu, Ming‐Tai Lin, Jou‐Kou Wang, Mei‐Hwan Wu +9 moreopenalex +1 more source