Results 61 to 70 of about 99,706,347 (248)

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Relationship between ZFHX3 SNP rs2106261 genotype and the inflammation markers neutrophil/lymphocyte (N/L) ratio, C-reactive protein (CRP) and interleukin-6 (IL-6).

, 2018
Relationship between ZFHX3 SNP rs2106261 genotype and the inflammation markers neutrophil/lymphocyte (N/L) ratio, C-reactive protein (CRP) and interleukin-6 (IL-6).
Chikaaki Motoda (401856), Kazuaki Chayama (128675), Hidenori Ochi (128649), Takehito Tokuyama (401850), Hiroya Matsumura (4641715), Hiroshi Kawazoe (4543114), Michitaka Amioka (4641721), Shunsuke Tomomori (4641724), Akinori Sairaku (401855), Yasuki Kihara (401869), Naoya Hironobe (610380), Yuko Onohara (4641727), Shou Okamura (5714858), Yukiko Nakano (401847), Yousaku Ookubo (5714855)   +14 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

C-Reactive Protein to Albumin Ratio: A Reliable Marker in Colorectal Cancer

, 2021
Aim:Postoperative complications after colorectal cancer surgery result in increased treatment costs, prolonged hospital stays and poor prognosis and reduce quality of life of the patients.
Mustafa Duman, Özlem Zeliha Sert, Orhan Uzun, Aziz Serkan Zenger, Emre Aray, Tolga Ölmez, Hilmi Bozkurt, Selçuk Gülmez, Erdal Polat   +8 more
core   +1 more source

Comparative effects of remifentanil and fentanyl on inflammatory stress response in mastectomy surgery with general anesthesia: A case series

Bali Journal of Anesthesiology, 2020
Malignancy associated with chronic inflammation and stress response events by the surgical procedure. The use of an opioid such as remifentanil can decrease stress response that may be measured by leukocyte, neutrophil-to-lymphocyte ratio (NLR), platelet-
Tjokorda Gde Agung Senapathi, I Made Subagiartha, I Gusti Agung Gede Utara Hartawan, Adi Dharma Thius   +3 more
doaj   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Prognostic Significance of Baseline Neutrophil to Lymphocyte Ratio and Lymphocyte to C-reactive Protein Ratio in COVID-19 Patients [PDF]

Objective: Neutrophil-to-lymphocyte and lymphocyte-to-C-reactive protein ratios are important prognostic indicators for disease severity measurement among coronavirus patients. To predict the disease severity, CURB-65 scores, and outcome after 14 days of
Yasmin, Rifat, Hussain, Huma, Afsar, Anum, Abidi, Syeda Turab Fatima, Shah, Syed Asim Ali, ul Qadir, Aziz   +5 more
core   +1 more source