Results 61 to 70 of about 993,506 (266)
The non-destructive classification of plant materials using optical inspection techniques has been gaining much recent attention in the field of agriculture research.
Jyothsna Konkada Manattayil +8 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Objective To explore the preventive effect of oral and intravenous administration of N-acetylcysteine(NAC) on contrast-induced nephropathy(CIN) in patients with mild renal impairment undergoing contrast-enhanced CT.Methods A total of 97 patients with ...
XU Xiao +3 more
doaj
MANC: A masked autoencoder neural cryptography based encryption scheme for CT scan images
Sharing medical images securely is very important towards keeping patients’ data confidential. In this paper we propose MANC: a Masked Autoencoder Neural Cryptography based encryption scheme for sharing medical images. The proposed technique builds upon
Kishore Kumar +2 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Objective: To determine diagnostic accuracy of quadruple phase helical computed tomography scan in detection of hepatocellular carcinoma in individuals with hepatitis B and C, keeping histopathology as the gold standard.
Saadia Sarwar Soomro +5 more
doaj +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
BackgroundMagnetic resonance imaging (MRI) of the brain in children and adolescents is a well-established method in both clinical practice and in neuroscientific research.
Charlotte Jaite +9 more
doaj +1 more source
Background During therapeutic beam irradiation, an unvisualized three-dimensional (3D) target position should be estimated using an external surrogate with an estimation model.
Hiraku Iramina +6 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source

