Results 61 to 70 of about 971,936 (265)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Different routes of N-acetylcysteineon administration in preventing contrast-induced nephropathy in mild renal impairment patients undergoing contrast-enhanced CT

Linchuang shenzangbing zazhi, 2015
Objective To explore the preventive effect of oral and intravenous administration of N-acetylcysteine(NAC) on contrast-induced nephropathy(CIN) in patients with mild renal impairment undergoing contrast-enhanced CT.Methods A total of 97 patients with ...
XU Xiao, HUANG Min, DU Li-guo, LI Xiao-ning   +3 more
doaj  

MANC: A masked autoencoder neural cryptography based encryption scheme for CT scan images

MethodsX
Sharing medical images securely is very important towards keeping patients’ data confidential. In this paper we propose MANC: a Masked Autoencoder Neural Cryptography based encryption scheme for sharing medical images. The proposed technique builds upon
Kishore Kumar, Sarvesh Tanwar, Shishir Kumar   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Diagnostic Performance of Quadruple Phase Multidetector Row Computed Tomography in Hepatoma: Comparison with Histopathological Diagnosis

Journal of the Dow University of Health Sciences, 2019
Objective: To determine diagnostic accuracy of quadruple phase helical computed tomography scan in detection of hepatocellular carcinoma in individuals with hepatitis B and C, keeping histopathology as the gold standard.
Saadia Sarwar Soomro, Muhammad Saad Ahmed, Sheeza Imtiaz, Waseem Mehmood Nizamani, Muhammad Kashif Shazlee, Saifullah Obaidullah   +5 more
doaj   +1 more source

Evaluation Of Ultrasonic C-Scan Images By Fractal Dimension

, 2012
{"references": ["B. B. Mandelbrot, and J. W. Wallis, \"Fractional Brownian Motions,\"\nFractional Noises and Applications, SIAM review, 10: 422-437, 1968.", "B. B. Mandelbrot, \"The Fractal Geometry of Nature,\" W. H. Freeman,\nSan Francisco, CA, 1982.", "A. P.
S. Samanta, D. Datta, S. S. Gautam
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

A comparison study of anxiety in children undergoing brain MRI vs adults undergoing brain MRI vs children undergoing an electroencephalogram.

PLoS ONE, 2019
BackgroundMagnetic resonance imaging (MRI) of the brain in children and adolescents is a well-established method in both clinical practice and in neuroscientific research.
Charlotte Jaite, Viola Kappel, Adriane Napp, Marcus Sommer, Gerd Diederichs, Bernhard Weschke, Birgit Spors, Arpad von Moers, Ulrike Lehmkuhl, Christian J Bachmann   +9 more
doaj   +1 more source

Optimization of training periods for the estimation model of three-dimensional target positions using an external respiratory surrogate

Radiation Oncology, 2018
Background During therapeutic beam irradiation, an unvisualized three-dimensional (3D) target position should be estimated using an external surrogate with an estimation model.
Hiraku Iramina, Mitsuhiro Nakamura, Yusuke Iizuka, Takamasa Mitsuyoshi, Yukinori Matsuo, Takashi Mizowaki, Ikuo Kanno   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source