Decreased plasma level of C-type lectin-like receptor 2 (CLEC-2) in patients with breast cancer. [PDF]
Chen CC +10 more
europepmc +1 more source
Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki +5 more
wiley +1 more source
B7 Family Molecule VSIG4 Regulates Pulmonary Anti-Influenza Immune Responses via C-Type Lectin Signal Pathway. [PDF]
Zhu J +14 more
europepmc +1 more source
Glyco‐Nanogels for Modulating Pseudomonas aeruginosa Biofilm
Nanogels presenting α‐galactose and β‐fucose can significantly alter Pseudomonas aeruginosa biofilm dynamics through their interaction with lectins. Application timing is crucial: pre‐treatment reduces biofilm, while treatment after biofilm initiation increases biomass.
Sophia Rosencrantz +4 more
wiley +1 more source
Phylogenetic and structural insights into the origin of C-type lectin Mincle in vertebrates. [PDF]
Ito T +6 more
europepmc +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Non-receptor tyrosine kinase c-Abl downstream of C-type lectin receptors regulates innate antifungal immunity through c-Cbl/MAPK pathway. [PDF]
Ma S-J +5 more
europepmc +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Amniotic fluid glycoproteins as potential ligands for macrophage galactose-type C-type lectin and their possible implications for immunoregulation during pregnancy. [PDF]
Szczykutowicz J +2 more
europepmc +1 more source
Inflammation, Immunity, and Cardiovascular Diseases
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo +8 more
wiley +1 more source

