Results 181 to 190 of about 171,997 (216)

Proteomic landscape of decellularized breast carcinomas identifies C-type lectin domain family 3 member A as a driver of cancer aggressiveness. [PDF]

NPJ Breast Cancer
Triulzi T, Giussani M, Maffioli E, Regondi V, Lorenc EJ, Arlotta V, Bianchi F, Pozzi S, Varricchio M, Cancila V, Valenti C, Sandri M, Podestà A, Sfondrini L, Vozzi G, Tedeschi G, Pupa SM, Tagliabue E.   +17 more
europepmc   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

Insect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo, João Alfredo Teodoro, Danilo T. Amaral   +2 more
wiley   +1 more source

Snake Venom C-Type Lectin-like Protein <i>Vaa</i>-Snaclec-3/2 Efficiently Prevents Carotid Artery Thrombosis in a Mouse Model Without Compromising Blood Coagulation. [PDF]

Toxins (Basel)
Žužek MC, Križaj I, Brvar M, Trobec T, Kranjc Brezar S, Dobaja Borak M, Leonardi A, Požek K, Vrecl M, Frangež R.   +9 more
europepmc   +1 more source

Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity

Immunology, EarlyView.
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez, Vania Aminta Zuleica López‐Esparza, Mariana Flores‐Castelán, Leopoldo Santos‐Argumedo   +3 more
wiley   +1 more source

The macrophage galactose-type C-type lectin 1 receptor plays a major role in mediating colitis-associated colorectal cancer malignancy. [PDF]

Immunol Cell Biol
Nieto-Yañez O, Navia SH, Juárez-Avelar I, Rodríguez T, Andrade-Meza A, Ortiz-Sánchez BJ, Mendoza-Rodríguez MG, Olguín JE, Reyes JL, Montes de Oca-Samperio D, Salinas Lara C, Terrazas LI, Rodriguez-Sosa M.   +12 more
europepmc   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Antithrombin regulates neutrophil activities through the stimulation of C-type lectin family 1A. [PDF]

Blood Vessel Thromb Hemost
Takahashi Y, Htwe SS, Wang D, Wake H, Yata M, Tomonobu N, Kinoshita R, Sakaguchi M, Nishibori M.   +8 more
europepmc   +1 more source

Advances in high‐resolution cryo‐volume electron microscopy (cvEM) imaging for unicellular and multicellular organisms

Journal of Microscopy, EarlyView.
Abstract Cryo‐Focused Ion Beam Scanning Electron Microscopy (cryoFIB‐SEM) using samples fixed by high‐pressure freezing uniquely enables high‐resolution cryo‐volume Electron Microscope (cvEM) images of cell ultrastructure to be obtained from whole cells and complex tissues in their near native state. As the freezing process also preserves fluorescence,
Maryna Kobylynska, Daniel Nicholls, Zoe Broad, Jack Wells, Alex Robinson, Stefania Marcotti, Damien McGrouther, Ch'ng Q‐L, Genoveva Esteban, Nigel Browning, Roland Fleck   +10 more
wiley   +1 more source

The importance of Fcγ and C-type lectin receptors in host immune responses during <i>Pneumocystis</i> pneumonia. [PDF]

Infect Immun
Kottom TJ, Carmona EM, Schaefbauer K, Stelzig KE, Pellegrino MR, Bindzus M, Limper AH.   +6 more
europepmc   +1 more source