Results 251 to 260 of about 237,325 (347)

TREM2 Downregulation Disrupts Microglial Function and Synaptic Pruning Through RA/RARα Signaling: Mechanisms Underlying Autism‐Like Behaviors

open access: yesPediatric Discovery, EarlyView.
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu   +9 more
wiley   +1 more source

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre   +3 more
wiley   +1 more source

Biochemical analysis of Caenorhabditis elegans surface mutants [PDF]

open access: yes, 1997
Blaxter, M.L., Link, C., Silverman, M.
core  

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Photopharmacology beyond azobenzene photoswitches

open access: yesResponsive Materials, EarlyView.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo   +5 more
wiley   +1 more source

Hemolytic C-Type Lectin CEL-III from Sea Cucumber Expressed in Transgenic Mosquitoes Impairs Malaria Parasite Development

open access: gold, 2007
Shigeto Yoshida   +6 more
openalex   +2 more sources

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