Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR. [PDF]
Omahdi Z +9 more
europepmc +1 more source
Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2
Joshua H. Bourne +8 more
doaj +1 more source
The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection. [PDF]
Liang J +14 more
europepmc +1 more source
C-type lectin receptor-mediated immune recognition and response of the microbiota in the gut. [PDF]
Li TH, Liu L, Hou YY, Shen SN, Wang TT.
europepmc +1 more source
Impact of Aging and HIV Infection on the Function of the C-Type Lectin Receptor MINCLE in Monocytes. [PDF]
Zapata HJ +9 more
europepmc +1 more source
Receptor-mediated gene delivery employing lectin-binding specificity [PDF]
Batra, R. K. +4 more
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C-Type Lectin Receptors in Phagocytosis
2020C-type lectin receptors (CLRs) are a family of transmembrane proteins having at least one C-type lectin-like domain (CTLD) on the cell surface and either a short intracellular signaling tail or a transmembrane domain that facilitates interaction with a second protein, often the Fc receptor common gamma chain (FcRγ), that mediates signaling.
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C-type lectin receptors in antifungal immunity
Trends in Microbiology, 2008Fungal infections represent a significant health burden, especially in immunocompromised individuals, yet many of the underlying immunological mechanisms involved in the recognition and control of these pathogens are unclear. The identification of the Toll-like receptors (TLRs) has shed new insights on innate microbial recognition and the initiation of
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C-Type Lectin Receptors in Antifungal Immunity
2020Most fungal species are harmless to humans and some exist as commensals on mucocutaneous surfaces. Yet many fungi are opportunistic pathogens, causing life-threatening invasive infections when the immune system becomes compromised. The fungal cell wall contains conserved pathogen-associated molecular patterns (PAMPs), which allow the immune system to ...
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