Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
Leishmania donovani Attenuates Dendritic Cell Trafficking to Lymph Nodes by Inhibiting C-Type Lectin Receptor 2 Expression via Transforming Growth Factor-β. [PDF]
Microbiol Spectr, 2023 Yadav M +7 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley +1 more source
Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C-type lectin receptor Langerin. [PDF]
Eur J Immunol, 2022 Bellmann L +19 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian +4 more
wiley +1 more source
C-type lectin receptor DCIR contributes to hippocampal injury in acute neurotropic virus infection. [PDF]
Sci Rep, 2021 Stoff M +10 more
europepmc +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Characterization of antifungal C-type lectin receptor expression on murine epithelial and endothelial cells in mucosal tissues. [PDF]
Eur J Immunol, 2021 Stappers MHT +6 more
europepmc +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
wiley +1 more source