The impact of temperature on the analysis of STD NMR ligand epitope mapping has been thoroughly investigated. For protein–ligand complexes under fast exchange kinetics, a negligible temperature effect is observed. For the intermediate exchange regime, VT‐STD NMR allows to obtain better discriminated epitope mappings, hence enabling the accurate ...
Gabriel Rocha +3 more
wiley +1 more source
Pathogen size alters C-type lectin receptor signaling in dendritic cells to influence CD4 Th9 cell differentiation. [PDF]
Oh S +7 more
europepmc +1 more source
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez +13 more
wiley +1 more source
CLR-Seq: A pipeline to identify bacterial microbiota species with immune-relevant glycan moieties through human C-type lectin receptor interaction. [PDF]
Mol J +7 more
europepmc +1 more source
A Novel C-Type Lectin Receptor-Targeted α-Synuclein-Based Parkinson Vaccine Induces Potent Immune Responses and Therapeutic Efficacy in Mice. [PDF]
Schmidhuber S +10 more
europepmc +1 more source
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Layilin at the crossroads of immunity and motility: a C-type lectin receptor in Hyaluronan Signaling. [PDF]
Mellema RA, Petrey AC.
europepmc +1 more source
Extracellular Nucleosomes Accelerate Microglial Inflammation via C-Type Lectin Receptor 2D and Toll-Like Receptor 9 in mPFC of Mice With Chronic Stress. [PDF]
Wu H +9 more
europepmc +1 more source
Granzyme K: A new frontier in systemic lupus erythematosus
The role of Granzyme K in the pathogenesis of systemic lupus erythematosus and its clinical translational significance. Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by dysregulated adaptive and innate immunity and aberrant complement activity.
Zhongyu Chen +5 more
wiley +1 more source

