Results 81 to 90 of about 115,349 (202)

Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]

, 1994
The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G., Berger, Eric G, Mechtler, Karl, Rusconi, Sandro, Wagner, Ernst, Birnstiel, Max L., Cotten, Matt, Clausen, Erik, Dinter, André, Thurnher, Martin, Berger, Erik G., Clausen, Henrik, Birnstiel, Max L   +12 more
core   +1 more source

Genetic variants in mannose receptor gene (MRC1) confer susceptibility to increased risk of sarcoidosis

BMC Medical Genetics, 2010
Background Mannose receptor (MR) is a member of the C-type lectin receptor family involved in pathogen molecular-pattern recognition and thought to be critical in shaping host immune response.
Hizawa Nobuyuki, Yamaguchi Etsuro, Gao Peisong, Taniguchi Natsuko, Shimizu Kenichi, Shimizu Kaoruko, Isada Akira, Takahashi Ayumu, Konno Satoshi, Hattori Takeshi, Huang Shau-Ku, Nishimura Masaharu   +11 more
doaj   +1 more source

A solution state NMR study of the structure and ligand binding properties of the human C-type lectin DC-SIGNR [PDF]

The protein DC-SIGNR (Dendritic-cell specific ICAM3 grabbing non-integrin related) is a C-type (calcium-dependent) lectin, which binds highly-branched mannose oligosaccharides.
Probert, Fay
core  

Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]

, 1998
The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, Antonio, Villalobo, A.   +2 more
core   +1 more source

CD69 is a TGF-β/1α,25-dihydroxyvitamin D3 target gene in monocytes

, 2013
CD69 is a transmembrane lectin that can be expressed on most hematopoietic cells. In monocytes, it has been functionally linked to the 5-lipoxygenase pathway in which the leukotrienes, a class of highly potent inflammatory mediators, are produced ...
Thea K Wöbke, Thea K. Wöbke, Bernd L. Sorg, Dieter Steinhilber, Wöbke, Thea Katharina, Andreas von Knethen, Bernd L Sorg, Sorg, Bernd L., Knethen, Andreas von, Steinhilber, Dieter   +9 more
core   +1 more source

Genetic variation in the C-type lectin receptor CLEC4M in type 1 von Willebrand Disease patients.

PLoS ONE, 2018
von Willebrand factor (VWF) levels in healthy individuals and in patients with type 1 von Willebrand disease (VWD) are influenced by genetic variation in several genes, e.g. VWF, ABO, STXBP5 and CLEC4M.
Eric Manderstedt, Christina Lind-Halldén, Stefan Lethagen, Christer Halldén   +3 more
doaj   +1 more source

Trimeric structure of the mouse Kupffer cell C‐type lectin receptor Clec4f

, 2019
International audienceThe C-type lectin receptor Clec4f has been identified as a specific surface marker for Kupffer cells, although its ortholog is absent in humans and its biological function remains elusive.
Zheng, Fang, Fang Zheng, Felix, Jan, Jinhong Zhou, Yingmei Pei, Irina Gutsche, M. Joanne Lemieux, Ouyang, Zhenlin, Ma, Bohan, Yurong Wen, Bohan Ma, Zhou, Jinhong, Zhenlin Ouyang, Hwang, Peter, Lemieux, M Joanne, Hwang, Peter M., Lemieux, M. Joanne, Pei, Yingmei, Wen, Yurong, Gutsche, Irina, Peter M. Hwang, Jan Felix   +21 more
core   +1 more source

The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species.

PLoS ONE, 2019
Phagocytosis is a receptor-mediated process critical to innate immune clearance of pathogens. It proceeds in a regulated sequence of stages: (a) migration of phagocytes towards pathogens, (b) recognition of PAMPs and binding through PRRs, (c) engulfment ...
Mohammed Haider, Ivy M Dambuza, Patawee Asamaphan, Mark Stappers, Delyth Reid, Sho Yamasaki, Gordon D Brown, Neil A R Gow, Lars P Erwig   +8 more
doaj   +1 more source

The Interaction of Human Pathogenic Fungi With C-Type Lectin Receptors

Frontiers in Immunology, 2018
Fungi, usually present as commensals, are a major cause of opportunistic infections in immunocompromised patients. Such infections, if not diagnosed or treated properly, can prove fatal. However, in most cases healthy individuals are able to avert the fungal attacks by mounting proper antifungal immune responses. Among the pattern recognition receptors
Surabhi Goyal, Surabhi Goyal, Juan Camilo Castrillón-Betancur, Juan Camilo Castrillón-Betancur, Esther Klaile, Hortense Slevogt   +5 more
openaire   +3 more sources

Monocyte galactose/N-acetylgalactosamine-specific C-type lectin receptor stimulant immunotherapy of an experimental glioma. Part II: combination with external radiation improves survival

, 2012
Sergiy V Kushchayev,1 Tejas Sankar,1 Laura L Eggink,5,6 Yevgeniya S Kushchayeva,5 Philip C Wiener,1,5 J Kenneth Hoober,5,6 Jennifer Eschbacher,3 Ruolan Liu,2 Fu-Dong Shi,2 Mohammed G Abdelwahab,4 Adrienne C Scheck,4 Mark C Preul11Neurosurgery Research ...
Wiener PC, Sankar T, Eschbacher J, Kushchayev SV, Shi FD, Eggink LL, Scheck AC, Kushchayeva YS, Hoober JK, Liu R, Preul MC, Abdelwahab MG   +11 more
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