Results 101 to 110 of about 25,168,555 (296)

Protocol to identify the ligand binding site of Mincle using NMR spectroscopy

STAR Protocols
Summary: Mincle (macrophage-inducible C-type lectin, CLEC4E) is a C-type lectin immune-stimulatory receptor that can be targeted for inducing potent adjuvant effects. Mincle can recognize trehalose dimycolate and related glycolipids.
Atsushi Furukawa, Hiroyuki Kumeta, Takashi Saitoh, Katsumi Maenaka   +3 more
doaj   +1 more source

A solution state NMR study of the structure and ligand binding properties of the human C-type lectin DC-SIGNR [PDF]

The protein DC-SIGNR (Dendritic-cell specific ICAM3 grabbing non-integrin related) is a C-type (calcium-dependent) lectin, which binds highly-branched mannose oligosaccharides.
Probert, Fay
core  

Molecular cloning and expression of a C-type lectin gene from Venerupis philippinarum [PDF]

, 2014
C-type lectins have been demonstrated to play important roles in invertebrate innate immunity by mediating the recognition of pathogens and clearing the micro-invaders.
Wang, Chunlin, Chen, Leilei, Mu, Changkao, Zhao, Jianmin   +3 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Comparative genomics of natural killer cell receptor gene clusters.

PLoS Genetics, 2005
Many receptors on natural killer (NK) cells recognize major histocompatibility complex class I molecules in order to monitor unhealthy tissues, such as cells infected with viruses, and some tumors.
James Kelley, Lutz Walter, John Trowsdale   +2 more
doaj   +2 more sources

Role of C-type Lectin Receptor to C.albicans on Promotion of Inflamantory Diseases

Denta, 2021
In early 2010 there was a very rapid progress in the development of immunity to fungi, i.e  the discovery of CLR. CLR is one of the PRR receptors found in immune cells that recognize the cell wall of fungi and then trigger a transduction signal that ...
Erna Sulistyani
doaj  

Genetic variants in mannose receptor gene (MRC1) confer susceptibility to increased risk of sarcoidosis

BMC Medical Genetics, 2010
Background Mannose receptor (MR) is a member of the C-type lectin receptor family involved in pathogen molecular-pattern recognition and thought to be critical in shaping host immune response.
Hizawa Nobuyuki, Yamaguchi Etsuro, Gao Peisong, Taniguchi Natsuko, Shimizu Kenichi, Shimizu Kaoruko, Isada Akira, Takahashi Ayumu, Konno Satoshi, Hattori Takeshi, Huang Shau-Ku, Nishimura Masaharu   +11 more
doaj   +1 more source

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]

, 2009
Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine, Kozar, Tibor, Kojima, Shuji, Gabius, Hans-Joachim, Unverzagt, Carlo   +4 more
core   +1 more source

C-type lectin-(like) fold

, 2021
Review on C-type lectin-(like) fold – protein-protein interaction patterns and utilization potential. The xls table shows PDB ids and basic characteristics of PDB structures containing at least one C-type lectin-(like) domain ...
Skalova, T (via Mendeley Data)
core   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source