Results 91 to 100 of about 24,419,878 (289)
Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma
Scientific ReportsThe mechanism by which glycans in pancreatic ductal adenocarcinoma (PDAC) interact with human endogenous lectins in the tumor microenvironment remains largely unknown.
Shuntaro Tsukamoto +9 more
doaj +1 more source
Parasites & Vectors, 2014 Background The studies on sialomes have shown that hematophagous mosquito saliva consists of a lot of pharmacologically active proteins, in which C-type lectins have been identified and regarded as an important component of saliva.
Jinzhi Cheng +5 more
doaj +1 more source
CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells
Advanced Science, EarlyView.AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu +6 more
wiley +1 more source
Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]
, 2011 Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
Lacina, Lukas +21 more
core +1 more source
Advanced Science, EarlyView.This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu +13 more
wiley +1 more source
Crotacetin, a novel snake venom C-type lectin, is homolog of convulxin
Journal of Venomous Animals and Toxins including Tropical Diseases, 2005 Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant similarity in their primary structures with C-type lectins of other animals, and also present a conserved ...
G. Rádis-Baptista +8 more
doaj +1 more source
C-type lectins in immunity to Mycobacterium tuberculosis
Frontiers in Bioscience, 2011 Tuberculosis (TB) remains one of the leading causes of death due to a single infectious agent, Mycobacterium tuberculosis, with nearly 2 million deaths per year (1). Most individuals exposed to the bacillus develop a nonpathological form, latent TB, with only a small minority (5 to 10%) developing active disease.
Antoine, Tanne, Olivier, Neyrolles
openaire +2 more sources
The Anatomical Record, EarlyView.Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende +9 more
wiley +1 more source
Recent insights into structures and functions of C-type lectins in the immune system. [PDF]
Curr Opin Struct Biol, 2015 The majority of the C-type lectin-like domains in the human genome likely to bind sugars have been investigated structurally, although novel mechanisms of sugar binding are still being discovered.
Drickamer K, Taylor ME.
europepmc +2 more sources
Domain and phylogenetic analysis of 105 C-type lectins identified in M.separata, using DoMosaics.
, 2022 Domain and phylogenetic analysis of 105 C-type lectins identified in M.separata, using DoMosaics. CTL_tree_domain.jpg is the CTL tree developed using DoMosaics. C_type_lectin_ID.txt shows the ID of C-type lectin genes in M.
Kakeru Yokoi (5627273)
core +1 more source