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Population‐Scale Plasma Proteomics Reveals Systemic Inflammatory Signatures Associated With Chronic Rhinosinusitis

open access: yes
Clinical &Experimental Allergy, EarlyView.
Dachan Kim   +3 more
wiley   +1 more source
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Allostery in C-type lectins

Current Opinion in Structural Biology, 2020
C-type lectins are the largest and most diverse family of mammalian carbohydrate-binding proteins. They share a common protein fold, which provides the unifying basis for calcium-mediated carbohydrate recognition. Their involvement in a multitude of biological functions is remarkable.
Keller, B., Rademacher, C.
openaire   +3 more sources

Genomic analysis of C-type lectins

Biochemical Society Symposia, 2002
Many biological effects of complex carbohydrates are mediated by lectins that contain discrete carbohydrate-recognition domains. At least seven structurally distinct families of carbohydrate-recognition domains are found in lectins that are involved in intracellular trafficking, cell adhesion, cell–cell signalling, glycoprotein turnover and innate ...
Kurt, Drickamer, Andrew J, Fadden
openaire   +2 more sources

C-Type Lectin Receptors in Phagocytosis

2020
C-type lectin receptors (CLRs) are a family of transmembrane proteins having at least one C-type lectin-like domain (CTLD) on the cell surface and either a short intracellular signaling tail or a transmembrane domain that facilitates interaction with a second protein, often the Fc receptor common gamma chain (FcRγ), that mediates signaling.
Kai, Li, David M, Underhill
openaire   +2 more sources

C-type lectin receptors in antifungal immunity

Trends in Microbiology, 2008
Fungal infections represent a significant health burden, especially in immunocompromised individuals, yet many of the underlying immunological mechanisms involved in the recognition and control of these pathogens are unclear. The identification of the Toll-like receptors (TLRs) has shed new insights on innate microbial recognition and the initiation of
Janet A, Willment, Gordon D, Brown
openaire   +2 more sources

C-Type Lectins

2014
C-type lectins belong to a superfamily of receptors that share structural homology in their carbohydrate recognition domains and often bind to carbohydrates in a Ca-dependent fashion. Whereas endocytic C-type lectin receptors (CLRs) trigger the receptor-mediated endocytosis of soluble ligands, myeloid CLRs in innate immunity act as pattern recognition ...
Timo Johannssen   +3 more
openaire   +1 more source

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