Results 61 to 70 of about 15,661 (180)

Characterization of Heme Uptake Proteins; HtaB, ChtB, and ChtA from Corynebacterium Diphtheriae Approaches to the Reaction of Dechloromonas Aromatica Chlorite Dismutase with Nitrite [PDF]

open access: yes, 2022
Heme is a source of iron for many pathogenic bacteria. Corynebacterium diphtheriae, the first protein in the system is HtaA, ChtA, and/or ChtC; heme is transferred to HtaB or ChtB. Heme is then mobilized into the cytosol by the ABC transporter where iron
Odhiambo, Catherine
core   +2 more sources

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

Image_2_Distinct Genomic Features Characterize Two Clades of Corynebacterium diphtheriae: Proposal of Corynebacterium diphtheriae Subsp. diphtheriae Subsp. nov. and Corynebacterium diphtheriae Subsp. lausannense Subsp. nov..TIFF [PDF]

open access: yes, 2018
Corynebacterium diphtheriae is the etiological agent of diphtheria, a disease caused by the presence of the diphtheria toxin. However, an increasing number of records report non-toxigenic C. diphtheriae infections. Here, a C.
Angela Koutsokera (288854)   +6 more
core   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, Volume 26, Issue 8, Page 9-28, August 2026.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Divergent evolution of Corynebacterium diphtheriae in India: An update from National Diphtheria Surveillance network.

open access: yesPLoS ONE, 2021
Diphtheria is caused by a toxigenic bacterium Corynebacterium diphtheria which is being an emerging pathogen in India. Since diphtheria morbidity and mortality continues to be high in the country, the present study aimed to study the molecular ...
Naveen Kumar Devanga Ragupathi   +13 more
doaj   +1 more source

CLINICO–Demographic Profile and Outcomes of Hospitalised Children With Diphtheria in A Tertiary Care Hospital of Peshawar

open access: yesActa Paediatrica, Volume 115, Issue 8, Page 1646-1653, August 2026.
ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad   +6 more
wiley   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia   +4 more
wiley   +1 more source

Molecular epidemiology of C. diphtheriae strains during different phases of the diphtheria epidemic in Belarus [PDF]

open access: yes, 2006
Background The reemergence of epidemic diphtheria in Belarus in 1990s has provided us with important information on the biology of the disease and the diversity of the causative agent Corynebacterium diphtheriae.
Titov, Leonid   +17 more
core   +1 more source

Non-toxigenic Corynebacterium diphtheriae endocarditis: A cluster of five cases

open access: yesSouthern African Journal of Infectious Diseases
Background: Classical toxin-mediated respiratory diphtheria has become less common because of widespread effective vaccination globally but invasive disease as a result of non-toxigenic strains of Corynebacterium diphtheriae is not prevented by ...
Tamsin Lovelock   +9 more
doaj   +1 more source

Effect of Topical Application of Antimicrobial Peptide PL‐5 (Peceleganan) Spray on Mild to Moderate Infection of Diabetic Foot Ulcers: A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial

open access: yesJournal of Diabetes, Volume 18, Issue 7, July 2026.
Topical PL‐5 spray improves clinical outcomes in mild‐to‐moderate infected diabetic foot ulcers and achieves superior pathogen clearance among drug‐resistant infection subgroups. It represents a promising low‐resistance topical option for managing mild to moderate DFU infections.
Li Qian   +10 more
wiley   +1 more source

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