Results 71 to 80 of about 19,770,630 (179)

Effect of Topical Application of Antimicrobial Peptide PL‐5 (Peceleganan) Spray on Mild to Moderate Infection of Diabetic Foot Ulcers: A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial

open access: yesJournal of Diabetes, Volume 18, Issue 7, July 2026.
Topical PL‐5 spray improves clinical outcomes in mild‐to‐moderate infected diabetic foot ulcers and achieves superior pathogen clearance among drug‐resistant infection subgroups. It represents a promising low‐resistance topical option for managing mild to moderate DFU infections.
Li Qian   +10 more
wiley   +1 more source

Percentage of PAI features along the genome and the pathogenicity islands of C. pseudotuberculosis and C. diphtheriae.

open access: yes, 2012
Percentage of PAI features along the genome and the pathogenicity islands of C. pseudotuberculosis and C. diphtheriae.
Eva Trost (104509)   +11 more
core   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan   +2 more
wiley   +1 more source

Integrated Molecular Docking and Gene Expression Analyses Suggest a Potential Interaction Between Diphtheria Toxin and Bcl‐2 in HT‐29 Colorectal Cancer Cells

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan   +3 more
wiley   +1 more source

Diphtheria Vaccination Coverage and Correlation With Multidimensional Poverty Among Children in Nigeria

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley   +1 more source

Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage

open access: yesBMC Microbiology, 2012
Background Corynebacterium ulcerans can cause a diphtheria-like illness, especially when the bacterium is lysogenized with a tox gene-carrying bacteriophage that produces diphtheria toxin. Acquisition of toxigenicity upon phage lysogenization is a common
Sekizuka Tsuyoshi   +8 more
doaj   +1 more source

Toxin gene truncation via IS1132 in non-toxigenic toxin gene-bearing (NTTB) Corynebacterium diphtheriae

open access: yesInternational Journal of Medical Microbiology
Background: Recently a Corynebacterium diphtheriae (C. diphtheriae) outbreak was reported in Europe described as the largest upsurge of cases in the last 70 years. Clinically relevant infections and transmission events are not necessarily associated only
Anna Dudakova   +13 more
doaj   +1 more source

Parameters for TraDIS data set derived from the non-toxigenic C. diphtheriae strain ISS 3319 transposon library.

open access: yes, 2023
Parameters for TraDIS data set derived from the non-toxigenic C. diphtheriae strain ISS 3319 transposon library.
Von Vergel L. Torres (15361420)   +9 more
core   +1 more source

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao   +24 more
wiley   +1 more source

In vitro Studies of Non-Diphtheriae Corynebacterium Isolates on Antimicrobial Susceptibilities, Drug Resistance Mechanisms, and Biofilm Formation Capabilities

open access: yesInfection and Drug Resistance, 2022
Wei Sun,* Liyan Ma,* Yana Li, Ying Xu, Jingjuan Wei, Lei Sa, Xinxin Chen, Jianrong Su Department of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China*These authors ...
Sun W   +7 more
doaj  

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