Results 71 to 80 of about 15,661 (180)

Detection of toxin-producing Corynebacterium diphtheriae from throat swabs of diphtheria patients using duplex real-time PCR

open access: yesIranian Journal of Microbiology, 2020
Background and Objectives: Diphtheria is a potentially fatal disease caused by toxigenic bacterial infection, particularly from Corynebacterium diphtheriae (C. diphtheriae). Isolation of C.
Yeva Rosana   +4 more
doaj   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan   +2 more
wiley   +1 more source

Integrated Molecular Docking and Gene Expression Analyses Suggest a Potential Interaction Between Diphtheria Toxin and Bcl‐2 in HT‐29 Colorectal Cancer Cells

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan   +3 more
wiley   +1 more source

Diphtheria Vaccination Coverage and Correlation With Multidimensional Poverty Among Children in Nigeria

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley   +1 more source

Population genomics and antimicrobial resistance in Corynebacterium diphtheriae [PDF]

open access: yes, 2020
Background: Corynebacterium diphtheriae, the agent of diphtheria, is a genetically diverse bacterial species. Although antimicrobial resistance has emerged against several drugs including first-line penicillin, the genomic determinants and population ...
Rodrigues, Carla   +29 more
core   +1 more source

Reaction intermediate rotation during the decarboxylation of coproheme to heme b in C. diphtheriae. [PDF]

open access: yesBiophys J, 2021
Sebastiani F   +8 more
europepmc   +2 more sources

Potential pathogenic role of aggregative- adhering Corynebacterium diphtheriae of different clonal groups in endocarditis

open access: yesBrazilian Journal of Medical and Biological Research, 2008
Invasive diseases caused by Corynebacterium diphtheriae have been described increasingly. Several reports indicate the destructive feature of endocarditis attributable to nontoxigenic strains.
R. Hirata Jr.   +8 more
doaj  

Changes in MLST profiles and biotypes of Corynebacterium diphtheriae isolates from the diphtheria outbreak period to the period of invasive infections caused by nontoxigenic strains in Poland (1950–2016)

open access: yesBMC Infectious Diseases, 2018
Background Corynebacterium diphtheriae is a re-emerging pathogen in Europe causing invasive infections in vaccinated persons and classical diphtheria in unvaccinated persons. In the presented study we analysed genetic changes in C.
Urszula Czajka   +4 more
doaj   +1 more source

Phenotypic and Genotypic Correlates of Penicillin Susceptibility in Nontoxigenic Corynebacterium diphtheriae, British Columbia, Canada, 2015–2018

open access: yesEmerging Infectious Diseases, 2020
In 2015, the Clinical and Laboratory Standards Institute (CLSI) updated its breakpoints for penicillin susceptibility in Corynebacterium species from
Jason Zou   +8 more
doaj   +1 more source

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