Results 201 to 210 of about 19,786,213 (303)

Inefficacy of a novel osmotic associative learning assay in C. elegans. [PDF]

BMC Res Notes
Li JH, Price KH, Nitabach MN.
europepmc   +1 more source

Overexpression of xanthine dehydrogenase extends lifespan in <i>C. elegans</i>. [PDF]

MicroPubl Biol
Chino A, Sugiyama A, Ohno H.
europepmc   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Canonical and noncanonical Hippo signaling in C. elegans. [PDF]

Genetics
Huynh L, Fakieh RA, Hendrix C, Powell RT, Reiner DJ.   +4 more
europepmc   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Synchronization properties in C. elegans: Relating behavioral circuits to structural and functional neuronal connectivity. [PDF]

PLoS Comput Biol
Sar GK, Patton A, Towlson E, Davidsen J.
europepmc   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

The FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr, Carmen M. Ramos, Chris D. Turner, Alexander A. Soukas, Sean P. Curran   +4 more
wiley   +1 more source

rRNA intermediates associate with nucleolar reshaping in C. elegans. [PDF]

Nucleic Acids Res
Cheng J, Liu L, Xu D, Chen Y, Kuang Y, Zheng A, Hong M, Huang X, Zhou X, Niu W, Zhao J, Huang X, Zhu C, Chen X, Feng X, Guang S.   +15 more
europepmc   +1 more source

The trimeric Shu complex in C. elegans is an ATPase that remodels RAD51 filaments in the homologous recombination‐associated DNA damage response

The FEBS Journal, EarlyView.
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu, Guangxin Xing, Kichang Paik, Anton Gartner, Hong Ling   +4 more
wiley   +1 more source

Heat stress promotes GTBP-1 association with perinuclear P-bodies in the C. elegans germline. [PDF]

PLoS Genet
Zang D, Jing Y, Huang X, Kuang Y, Cheng J, Wang W, Xu D, Zhu C, Chen D, Zhao Z, Feng X, Guang S.   +11 more
europepmc   +1 more source