Results 101 to 110 of about 18,702,394 (209)

Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies Are a Risk Factor for Central Nervous System Infection by Cryptococcus gattii in Otherwise Immunocompetent Patients

mBio, 2014
Cryptococcosis is caused by either Cryptococcus neoformans or C. gattii. While cryptococcal meningoencephalitis is caused mostly by C. neoformans in immunocompromised patients, the risk factors remain unclear for patients with no known immune defect ...
Tomomi Saijo, Jianghan Chen, Sharon C.-A. Chen, Lindsey B. Rosen, Jin Yi, Tania C. Sorrell, John E. Bennett, Steven M. Holland, Sarah K. Browne, Kyung J. Kwon-Chung   +9 more
doaj   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

Plant Biotechnology Journal, Volume 24, Issue 9, Page 5131-5151, September 2026.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng, Huan Li, Jun Wang, Li‐Chao Wang, Hui‐Zi Liu, Xiao‐Feng Dai, Steven J. Klosterman, Jie‐Yin Chen, Krishna V. Subbarao, Feng‐Mao Chen, Dan‐Dan Zhang   +10 more
wiley   +1 more source

Molecular identification of Cryptococcus neoformans serotypes36783

, 2007
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections primarily in immunocompromised hosts. Based on the genetic characteristics and serologic properties of capsular polysaccharides, three varieties and five serotypes have ...
F. Symoens, J. Bolognini, A. Enache-Angoulvant, C. Douchet, J. Chandenier, P. Lacube, J.L. Poirot, C. Hennequin   +7 more
core   +1 more source

HIV infection enhances vomocytosis of C. neoformans.

, 2020
Human monocyte-derived macrophages were infected with HIV and subsequently infected with C. neoformans. Time-lapse microscopy videos were manually scored for vomocytosis (top), uptake (middle) and intracellular proliferation rate of C. neoformans (bottom)
David Stirling (2154955), Robin C. May (6746873), Paula I. Seoane (8501175), Mahdad Noursadeghi (154756), Dalan Bailey (193037), Leanne M. Taylor-Smith (5040272), Lucy C. K. Bell (8501178)   +6 more
core   +1 more source

Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features [PDF]

, 2011
In this work, we biochemically characterized inositol phosphosphingolipid-phospholipase C (Isc1) from the pathogenic fungus Cryptococcus neoformans. Unlike Isc1 from other fungi and parasites which hydrolyze both fungal complex sphingolipids (IPC-PLC ...
Maurizio Del Poeta, Henry, Jennifer, Jennifer Henry, Luberto, Chiara, Chiara Luberto, Del Poeta, Maurizio, Guillotte, Aimee, Aimee Guillotte   +7 more
core   +1 more source

Caracterización molecular de cepas del complejo Cryptococcus neoformans-Cryptococcus gattii aisladas del líquido cefalorraquídeo

, 2013
La criptococosis es una infección fúngica causada por levaduras capsuladas del género Cryptococcus, particularmente las que se encuentran dentro del denominado complejo Cryptococcus neoformans- Cryptococcus gattii.
Sosa, María de los Ángeles, Fernández, Mariana Soledad, Cattana, María Emilia   +2 more
core  

Superoxide dismutase in Cryptococcus neoformans varieties gattii, grubi, and neoformans

, 2006
Some clear dissimilarities occur among the varieties of Cryptococcus neoformans but there are few studies about the differences among individual yeast antioxidant enzymes.
Dias, ALT, M. R. P. L. Brigagão, C. R. Paula, A. L. T. Dias, MRPL Brigagão, A. M. Siqueira, Colepicolo, P, Brigagão, MRPL, E. G. Silva, P. Colepicolo, ALT Dias, P Colepicolo, CR Paula, Paula, CR, AM Siqueira, EG da Silva, Siqueira, AM, Silva, EG da   +17 more
core   +1 more source

Inhibition of guanosine biosynthesis sensitizes C. neoformans to AmB.

, 2014
(A) E-Test of C. neoformans wt on AM3 medium (B) AM3 medium supplemented with 3.25 µg/mL MPA and (C) E-test analysis for AmB susceptibility of C. neoformans wt on AM3 supplemented with 3.25 µg/mL MPA and 20 µg/mL exogenous guanine.
John C. Panepinto (341607), Dithi Banerjee (516995), Lauren Burkard (516996)   +2 more
core   +1 more source

Host–Pathogen Interactions and Correlated Factors That Are Affected in Replicative-Aged Cryptococcus neoformans

Journal of Fungi
Cryptococcus neoformans is a facultative intracellular fungal pathogen. Ten-generation-old (10GEN) C. neoformans cells are more resistant to phagocytosis and killing by macrophages than younger daughter cells.
Vanessa K. A. Silva, Sungyun Min, Kyungyoon Yoo, Bettina C. Fries   +3 more
doaj   +1 more source

Cryptococcus neoformans induces IL-8 secretion and CXCL1 expression by human bronchial epithelial cells

Respiratory Research, 2008
Background Cryptococcus neoformans (C. neoformans) is a globally distributed fungal pathogen with the potential to cause serious disease, particularly among immune compromised hosts.
Badawy Mohamed, Carroll Scott F, Guillot Loïc, Qureshi Salman T   +3 more
doaj   +1 more source