Results 81 to 90 of about 18,702,394 (209)
Role of the Anaphase-Promoting Complex Activator Cdh1 in the Virulence of Cryptococcus neoformans
Journal of FungiCryptococcus neoformans is a globally distributed human fungal pathogen that can cause cryptococcal meningitis with high morbidity and mortality. In this study, we identified an anaphase-promoting complex (APC) activator, Cdh1, and examined its impact on
Qiu-Hong Liao +4 more
doaj +1 more source
FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The C. neoformans Mac1 Protein Is Polymorphic
, 2013 Translated amino acid sequences for Mac1 from strains B3501α and JEC21α (congenic to B3502a) are depicted. CNG02270 contains a copper-fist DNA binding domain at the N-terminus that is conserved between copper-regulating transcription factors, such as ...
Joseph Heitman (22335) +3 more
core +1 more source
Nanoscale Research Letters, 2018 Background Cryptococcus neoformans is an encapsulated yeast. There is still little quick and effective solution for the diagnosis or treatment of C. neoformans infection at an early stage in clinical.
Qin Xiao +7 more
doaj +1 more source
The Role of Testosterone and Gibberellic Acid in the Melanization of Cryptococcus neoformans
Frontiers in Microbiology, 2020 Cryptococcus neoformans, a spore-producing pathogenic yeast, affects immunocompromised individuals causing meningoencephalitis. Once C. neoformans is introduced via the respiratory tract, it is engulfed by macrophages and other phagocytes.
Jamila S. Tucker +4 more
doaj +1 more source
MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats
Advanced Science, Volume 13, Issue 49, 3 September 2026.The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen +13 more
wiley +1 more source
Identification and characterization of an aspartyl protease from Cryptococcus neoformans [PDF]
, 2007 Cryptococcosis, caused by Cryptococcus neoformans, is an invasive infection often occurring in AIDS patients. Potent therapy against HIV, which includes protease inhibitors (PIs), has beneficial effects also on opportunistic infections by pathogens such ...
GIBELLINI, Lara +15 more
core +1 more source
Advanced Science, Volume 13, Issue 53, 24 September 2026.Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su +7 more
wiley +1 more source
Human plasma-like medium (HPLM) induces Cryptococcus neoformans in vivo cell morphologies
mSphereThe fungal pathogen Cryptococcus neoformans (C. neoformans) forms yeast cells of different sizes and morphological characteristics during infection. These features are usually not seen in standard laboratory in vitro conditions. Here, we describe in vivo
Eduardo G. Mozo +4 more
doaj +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 2006 Cryptococcosis has been a significant cause of morbidity and mortality in patients with Aids. Many reservoirs of the agent Cryptococcus neoformans have been reported, but the ecology of this yeast must be elucidated in order to establish surveillance ...
Francisco de Assis Baroni +6 more
doaj +1 more source