Results 71 to 80 of about 33,016 (225)

Characterizing the role of DNA polymerase gamma in the yeast, Cryptococcus neoformans [PDF]

, 2017
The basidiomycetous yeast, Cryptococcus neoformans, is an opportunistic pathogen that is responsible for a common fungal infection of the central nervous system, cryptococcal meningoencephalitis. This is a signal disease of AIDs patients that can also be
NC DOCKS at Western Carolina University, Boggs, Joshua Ellis   +1 more
core  

A Straightforward Synthesis of a Diene From a Homoallylic Bromide to Access Cycloadducts to Elucidate Michael Acceptors as Antimicrobial Motifs

ChemistrySelect, Volume 11, Issue 25, 3 July 2026.
A straightforward method to cleanly yield a novel diene from isopulegol was developed. The diene served as a precursor to various cycloadducts, which led to the identification of Michael acceptors as antimicrobial motifs. ABSTRACT Conjugated dienes are useful precursors to cascade reactions that undergo cycloadditions to access polycyclic compounds ...
Jose G. Urbiola, Caroline Laughlin‐Black, Jace Salgado, Kaitlyn Varela, Hadi D. Arman, Catherine A. Wakeman, Francis K. Yoshimoto   +6 more
wiley   +1 more source

Role of the Anaphase-Promoting Complex Activator Cdh1 in the Virulence of Cryptococcus neoformans

Journal of Fungi
Cryptococcus neoformans is a globally distributed human fungal pathogen that can cause cryptococcal meningitis with high morbidity and mortality. In this study, we identified an anaphase-promoting complex (APC) activator, Cdh1, and examined its impact on
Qiu-Hong Liao, Lian-Tao Han, Meng-Ru Guo, Cheng-Li Fan, Tong-Bao Liu   +4 more
doaj   +1 more source

Molecular characterization of environmental Cryptococcus neoformans isolated in Vitoria, ES, Brazil Caracterização molecular de cepas ambientais de Cryptococcus neoformans isoladas em Vitória, ES, Brasil

Revista do Instituto de Medicina Tropical de São Paulo, 2008
Cryptococcus neoformans is the major cause of fungal meningitis, a potentially lethal mycosis. Bird excreta can be considered a significant environmental reservoir of this species in urban areas, thirty-three samples of pigeon excreta were collected ...
Mariceli Araujo Ribeiro, Popchai Ngamskulrungroj   +1 more
doaj   +1 more source

Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection. [PDF]

PLoS ONE, 2012
Cryptococcal meningoencephalitis is the most common fungal disease in the central nervous system. The mechanisms by which Cryptococcus neoformans invades the brain are largely unknown. In this study, we found that C.
Sheng-He Huang, Chun-Hua Wu, Yun C Chang, Kyung J Kwon-Chung, Robert J Brown, Ambrose Jong   +5 more
doaj   +1 more source

Insights Into the Susceptibility of Fungal Infection and STAT3 Genetic Mutations

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor that regulates a spectrum of genes and signalling pathways critical for the antifungal immune response. Mutations in the STAT3 gene confer susceptibility to severe and recurrent fungal infections, predominantly via disruption of interleukin‐17 (IL‐17 ...
Fengming Li, Xiaodong Liu, Yuanyuan Li, Jie Wu, Ningning Dang, Jing Guo   +5 more
wiley   +1 more source

Illuminating Choices for Library Prep: A Comparison of Library Preparation Methods for Whole Genome Sequencing of Cryptococcus neoformans Using Illumina HiSeq. [PDF]

, 2014
The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the major sequencing technology companies annually.
Mathew A Beale, Fisher, Matthew C, Rhodes Johanna, Matthew C Fisher, Rhodes, Johanna, Beale Mathew A., Fisher, MC, Beale, Mathew A, Fisher, Matthew C., Beale, Mathew A., Fisher Matthew C., Beale, MA, Rhodes, J, Johanna Rhodes, Rhodes, Johanna; id_orcid   +14 more
core   +1 more source

Cryptococcus neoformans carried by Odontomachus bauri ants

Memorias do Instituto Oswaldo Cruz, 2012
Cryptococcus neoformans is the most common causative agent of cryptococcosis worldwide. Although this fungus has been isolated from a variety of organic substrates, several studies suggest that hollow trees constitute an important natural niche for C ...
Mariana Santos de Jesus, William Costa Rodrigues, Glaucia Barbosa, Luciana Trilles, Bodo Wanke, Márcia dos Santos Lazéra, Manuela da Silva   +6 more
doaj   +1 more source

Monocyte dysfunction in patients with acquired immunodeficiency syndrome (AIDS) versus Cryptococcus neoformans

, 1997
In the present study we investigated the response of monocytes from AIDS patients, susceptible to cryptococcosis (
Monari C, Vecchiarelli A, Tascini C, Retini C, Bistoni F, Baldelli F, Pietrella D, Francisci D   +7 more
core   +1 more source

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
Ruthenium(II) (Ru(II)) pyrazolyl–pyridine half‐sandwich complexes (C1–C6) were synthesized and structurally characterized as prospective metalloantibiotics. Screening through the Community for Open Antimicrobial Drug Discovery (CO‐ADD) revealed selective activity against Acinetobacter baumannii, with favorable cytotoxicity profiles. Biophysical studies
M. Cassiem Joseph, Sheldon Sookai, Monika Nowakowska, Rotondwa Mphephu, Angela M. Kavanagh, Johannes Zuegg, Mark A. T. Blaskovich, Andrew J. Swarts   +7 more
wiley   +1 more source