Results 61 to 70 of about 33,016 (225)

CARD9 Is Required for Classical Macrophage Activation and the Induction of Protective Immunity against Pulmonary Cryptococcosis

mBio, 2020
Caspase recruitment domain-containing protein 9 (CARD9) is a critical adaptor molecule triggered by the interaction of C-type lectin receptors (CLRs) with carbohydrate motifs found in fungi.
Althea Campuzano, Natalia Castro-Lopez, Amanda J. Martinez, Michal A. Olszewski, Anutosh Ganguly, Chrissy Leopold Wager, Chiung-Yu Hung, Floyd L. Wormley   +7 more
doaj   +1 more source

Effects of Cryptococcus neoformans on activation of human alveolar basal epithelial adenocarcinoma cells (A549 cells)

Revista Médica de Minas Gerais
Introduction: The bronchial epithelium has defense mechanisms based on innate immunity against various airborne microorganisms, including Cryptococcus neoformans. Purpose: We evaluated the inflammatory effects of C.
Karina Cristina da Cruz Freitas, Wanessa Maria Santos, Aline Beatriz Mahler Pereira, Leonardo Euripedes Andrade-Silva, Paulo Roberto da Silva, Mario Leon Silva Vergara, Alexandre de Paula Rogerio   +6 more
doaj   +1 more source

The Role of Testosterone and Gibberellic Acid in the Melanization of Cryptococcus neoformans

Frontiers in Microbiology, 2020
Cryptococcus neoformans, a spore-producing pathogenic yeast, affects immunocompromised individuals causing meningoencephalitis. Once C. neoformans is introduced via the respiratory tract, it is engulfed by macrophages and other phagocytes.
Jamila S. Tucker, Jamila S. Tucker, Tiffany E. Guess, Tiffany E. Guess, Erin E. McClelland   +4 more
doaj   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng, Huan Li, Jun Wang, Li‐Chao Wang, Hui‐Zi Liu, Xiao‐Feng Dai, Steven J. Klosterman, Jie‐Yin Chen, Krishna V. Subbarao, Feng‐Mao Chen, Dan‐Dan Zhang   +10 more
wiley   +1 more source

Role of IL-17A on Resolution of Pulmonary C. neoformans Infection

PLoS ONE, 2011
The current studies evaluated the role of interleukin (IL)-17A in the induction of protective immunity against pulmonary cryptococcosis in mice. Protection against pulmonary infection with C. neoformans strain H99γ was associated with increased IL-17A production.
Wozniak, Karen L, Hardison, Sarah E, Kolls, Jay K, Wormley, Floyd L   +3 more
openaire   +5 more sources

Quantitative analysis of septin Cdc10 & Cdc3-associated proteome during stress response in the fungal pathogen Cryptococcus neoformans.

PLoS ONE
Cryptococcus neoformans is a pathogenic basidiomycetous yeast that primarily infects immunocompromised individuals. Fatal outcome of cryptococcosis depends on the ability of C. neoformans to sense and adapt to 37°C.
Stephani Martinez Barrera, Emma Hatchell, Stephanie D Byrum, Samuel G Mackintosh, Lukasz Kozubowski   +4 more
doaj   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

In vitro susceptibility to antifungal agents of environmental Cryptococcus spp. isolated in the city of Ribeirão Preto, São Paulo, Brazil

Memorias do Instituto Oswaldo Cruz, 2006
Infections by Cryptococcus strains other than C. neoformans have been detected in immunocompromised patients. Of these strains, three are considered human pathogens: C. albidus, C. laurenttii, and C. uniguttulatus.
Reginaldo dos Santos Pedroso, Joseane Cristina Ferreira, Regina Celia Candido   +2 more
doaj   +1 more source

Crecimiento del complejo Cryptococcus neoformans/ Cryptococcus gattiien extractos de excretas de palomas

Entramado, 2020
Cryptococcus neoformans/Cryptococcus gattii son agentes etiológicos de la criptococosis, el primero tiene distribución mundial y su hábitat principal son las excretas de palomas (Columba livia), mientras que el último se ha aislado de árboles y en pocas ...
Luz Dary Caicedo Bejarano, María Inés Álvarez   +1 more
doaj   +1 more source

Decoding the Structural Complexity of Fungal α‐ and β‐Glucan Matrix via Statistical Analysis of Solid‐State NMR Chemical Shifts

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
Solid‐state NMR combined with principal component analysis enables quantitative classification of fungal α‐ and β‐glucan architectures in intact cell walls, revealing conserved triple‐helical β‐1,3‐glucan conformations across species and predominantly bundled‐sheet α‐1,3‐glucan assemblies with condition‐dependent polymorphism. Statistical clustering of
Ankur Ankur, Cameron S. Vojvodin, Debkumar Debnath, Tuo Wang   +3 more
wiley   +1 more source