Results 51 to 60 of about 17,360 (163)

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

open access: yes, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose   +7 more
core   +1 more source

Differentiation of Candida parapsilosis, C. orthopsilosis, and C. metapsilosis by specific PCR amplification of the RPS0 intron

open access: yesInternational Journal of Medical Microbiology, 2011
Although Candida parapsilosis is the most prevalent among the 3 species of the *psilosis group, studies applying DNA-based diagnostic techniques with isolates previously identified as C. parapsilosis have revealed that both C. orthopsilosis and C. metapsilosis account for 0-10% of all these isolates, depending on the geographical area.
del Pilar Vercher, M.   +6 more
openaire   +4 more sources

Different risk factors for candidemia occur for Candida species belonging to the C. parapsilosis complex [PDF]

open access: yesMedical Mycology, 2014
Previous studies have demonstrated reduced virulence in the species that comprise the Candida parapsilosis complex. We investigated a cohort of 93 patients with candidemia caused by this complex. Most infections were caused by C. parapsilosis (80.6%), followed by C. orthopsilosis (18.3%) and C. metapsilosis (1.1%). Renal failure (P < 0.001) and chronic
C C, Constante   +8 more
openaire   +2 more sources

Design of species-specific primers for rapid detection and identification of Candida parapsilosis sensu stricto

open access: yesActa Biologica Slovenica, 2020
Candida species are the cause of approximately two million cases of candidiasis yearly worldwide, and are frequently involved in life-threatening infections.
Monika Novak Babič, Nina Gunde-Cimerman
doaj   +1 more source

Molecular identification of Candida orthopsilosis isolated from blood culture. [PDF]

open access: yes, 2008
The incidence of candidemia and invasive candidiasis have increased markedly due to the increasing number of immunocompromised patients. There are five major medically important species of Candida with their frequency of isolation in the diminishing ...
Chong, Pei Pei   +4 more
core   +1 more source

Synovial interleukin‐6 point‐of‐care testing, alone and combined with D‐dimer, supports rapid diagnosis of periprosthetic joint infection

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Data on the reliability of point‐of‐care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) D‐dimer (DD), interleukin 6 (IL‐6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL‐6 and PCT in ...
Sujeesh Sebastian   +6 more
wiley   +1 more source

Standardization of polymerase chain reaction for detection of fluconazole resistance targeting Y132F mutation in ERG11 gene in Candida parapsilosis [PDF]

open access: yesCurrent Medical Mycology
Background and Purpose: Candida parapsilosis is the third most commonly isolated species from candidemia patients admitted to Indian intensive care units.
Kanagasabapathi Karthika   +3 more
doaj   +1 more source

Host Transcriptomics and Culture‐Independent Testing for the Management of Febrile Neutropenia: Data From an Observational Study Conducted in a Bone Marrow Transplant Unit

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Managing febrile neutropenia is challenging due to the limited sensitivity of blood culture (BC) and the lack of tools differentiating infectious from non‐infectious fever. T2 magnetic resonance (T2MR) is a culture‐independent system detecting bacteria (T2Bacteria) and yeasts (T2Candida); SeptiCyte RAPID is a host response assay ...
Anna Maria Peri   +6 more
wiley   +1 more source

First report of monomicrobial Candida parapsilosis necrotizing fasciitis

open access: yesTransplant Infectious Disease, 2016
AbstractCandida parapsilosis is an emerging pathogen worldwide. It commonly causes soft tissue infection; however, to our knowledge there has been no previous report of monomicrobial necrotizing soft tissue infection (NSTI) secondary to C. parapsilosis. We report the first case of NSTI caused by C.
Gassiep, I.   +2 more
openaire   +3 more sources

Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris

open access: yesInternational Journal of Molecular Sciences, 2023
Antimicrobial peptides (AMPs) represent a promising class of therapeutic biomolecules that show antimicrobial activity against a broad range of microorganisms, including life-threatening pathogens. In contrast to classic AMPs with membrane-disrupting activities, new peptides with a specific anti-biofilm effect are gaining in importance since biofilms ...
Valerie Amann   +15 more
openaire   +3 more sources

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