Results 131 to 140 of about 13,656 (181)

A study of reactions to Corynebacterium Parvum (C. parvum) in the brain and dermis of the rat

Acta Neuropathologica, 1982
A comparative analysis was made of the histological changes caused by Corynebacterium Parvum (C. parvum) infected into the brain and dermis of normal and C. parvum presensitized rats. Control rats were injected with saline. It was shown that for approximately 3 days after the intracerebral injection the brain reacted with a polymorphonuclear cell ...
H M, Cravioto, G M, Hochwald, J, Ransohoff   +2 more
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C. parvum in germ-free mice

Cancer Immunology Immunotherapy, 1978
The effect of previous sensitization to C. parvum, by cross-reacting antigens from other bacteria, on the immunostimulatory effects of C. parvum treatment were studied in germ-free and conventional mice. It was found that the development of splenomegaly and specific delayed hypersensitivity following C.
M.T. Scott, T.T. MacDonald, P.B. Carter
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Characterization and potential use of a Cryptosporidium parvum virus (CPV) antigen for detecting C. parvum oocysts

Journal of Microbiological Methods, 2004
The purpose of this study was to characterize the viral symbiont (CPV) of Cryptosporidium parvum sporozoites and evaluate the CPV capsid protein (CPV40) as a target for sensitive detection of the parasite. Recombinant CPV40 was produced in Escherichia coli, purified by affinity chromatography, and used to prepare polyclonal rabbit sera specific for the
K E, Kniel, J A, Higgins, J M, Trout, R, Fayer, M C, Jenkins   +4 more
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C. Parvum immunotherapy of transplanted rat tumours

International Journal of Cancer, 1977
AbstractC. parvum (Wellcome CN 6134) has been tested for tumour suppression against a range of syngeneically transplanted rat tumours, both carcinogen‐induced and of spontaneous origin. Subcutaneous growth was not prevented by distant subcutaneous or intravenous injection of the preparation, although growth rates were sometimes depressed or accelerated.
M V, Pimm, R W, Baldwin
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Cryptosporidium erinacei and C. parvum in a group of overwintering hedgehogs

European Journal of Protistology, 2016
This study describes cryptosporidiosis in an overwintering group of 15 European hedgehogs (Erinaceus europaeus), comprising 3 adults and 12 juveniles. Four juvenile hedgehogs were hospitalised with anorexia, malodorous diarrhoea and dehydration. Immediate parasitological examinations revealed the presence of Cryptosporidium sp.
Lada, Hofmannová, Karel, Hauptman, Kristýna, Huclová, Dana, Květoňová, Bohumil, Sak, Martin, Kváč   +5 more
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CHARACTERIZATION OF SUBTILASE PROTEASE IN CRYPTOSPORIDIUM PARVUM AND C. HOMINIS

Journal of Parasitology, 2007
Cryptosporidium spp., enteropathogens of humans and other animals, are members of the Apicomplexa. In parasites belonging to this phylum, proteases have been shown to play a key role in the invasion of host cells, organelle biogenesis, and intracellular survival. The subtilases constitute a family of serine proteases present in prokaryotes, eukaryotes,
Xiaochuan, Feng, Donna E, Akiyoshi, Giovanni, Widmer, Saul, Tzipori   +3 more
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Immunogenicity, macrophage sensitivity, and therapeutic response to C. parvum of fibrosarcomas induced in C. parvum-treated and untreated mice

Cancer Immunology Immunotherapy, 1982
No correlation has been observed between the therapeutic response of isogeneic transplants of methylcholanthrene-induced murine fibrosarcomas to Corynebacterium parvum (CP) and the sensitivity of the tumour cells to the cytotoxic action of CP-activated macrophages (Mo) in vitro.
Woodruff, M, Forbes, G, Gordon, J
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Kinetics of Cryptosporidium parvum-specific cytokine responses in healing and nonhealing murine models of C. parvum infection

Parasitology Research, 2005
Susceptibility or resistance to infection with Cryptosporidium parvum correlates with the ability of mice to produce characteristic panels of cytokines in response to infection. Both adult healing and nonhealing mouse models of cryptosporidiosis were used to study the cell-mediated immune response during the course of C. parvum infection.
Singh, Inderpal, Theodos, Cynthia, Li, Wenjun, Tzipori, Saul   +3 more
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Immunoprophylaxis and immunotherapy for a murine fibrosarcoma with C. Granulosum and C. Parvum

International Journal of Cancer, 1974
AbstractProphylactic and therapeutic effectiveness of killed C. granulosum and C. parvum bacteria was investigated against a methylcholanthrene‐induced fibrosarcoma in syngeneic C3Hf/Bu mice. Subcutaneous or intravenous treatment of mice with 0.25 mg of these bacteria greatly reduced the number of tumor nodules (metastases, colonies) in the lung ...
Milas, L, Gutterman, J U, Basic, I, Hunter, N, Mavligit, G M, Hersh, V M, Withers, H R   +6 more
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The Effect of C. Parvum Therapy on Intratumoral Macrophage Subpopulations

1982
Systemic administration of Corynebacterium parvum can cause partial or in a few instances complete (1,2) regression of subcutaneously growing transplanted tumors (3). It is reasonable to suggest that tumor regression of this kind is macrophage mediated in light of the knowledge that C.
W H, McBride, K, Moore
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