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Effects of whole body irradiation in mice treated with C. parvum
European Journal of Cancer (1965), 1979Abstract We have investigated the effect of whole body irradiation (WBI) upon the survival of Corynebacterium parvum ( C. parvum )-treated CBA mice. Applied to mice 7 days after C. parvum WBI with 350–950 rad of X-ray killed more C. parvum -treated than -untreated mice.
Basic, I, Milas, L
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Cryptosporidium parvum Development in the BS-C-1 Cell Line
The Journal of Parasitology, 1998Cryptosporidium parvum is a worldwide parasitic protozoon capable of causing life-threatening disease in immunocompromised patients. In vitro cultivation of C. parvum has been under investigation for development of a well-defined in vitro model for C. parvum infectivity assay. This is the first report of C.
M Q, Deng, D O, Cliver
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The American journal of tropical medicine and hygiene, 1999
A 50% infectious dose (ID50) of 132 Cryptosporidium parvum oocysts was previously determined in serologically negative individuals (ELISA). In this study, 17 healthy adults with pre-existing anti-C. parvum serum IgG were challenged with 500-50,000 oocysts. Infection and diarrhea were associated with the higher challenge doses.
C L, Chappell +5 more
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A 50% infectious dose (ID50) of 132 Cryptosporidium parvum oocysts was previously determined in serologically negative individuals (ELISA). In this study, 17 healthy adults with pre-existing anti-C. parvum serum IgG were challenged with 500-50,000 oocysts. Infection and diarrhea were associated with the higher challenge doses.
C L, Chappell +5 more
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A comparison of the antitumour activities of glucans and C. parvum.
Developments in biological standardization, 1978After i.v. injection of glucans (yeast cell walls, lentinan and pseudonigeran) into CBA mice, the peritoneal macrophages became cytostatic to R1 leukemia cells in vitro, and the mice showed resistance to lung nodule formation by i.v. injected T3 fibrosarcoma cells. The glucans were less active than C. parvum.
R, Bomford, C, Moreno
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Anticancer research, 1992
In vitro culture of murine spleen cells with Corynebacterium parvum (C. parvum) was found to induce lymphokine-activated killer (LAK)-like cells capable of killing both natural killer (NK)-sensitive and NK-resistant tumor cells as well as syngeneic macrophages (M phi). The induction of LAK-like activity by C.
M F, Chen, H, Suzuki, S, Yano
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In vitro culture of murine spleen cells with Corynebacterium parvum (C. parvum) was found to induce lymphokine-activated killer (LAK)-like cells capable of killing both natural killer (NK)-sensitive and NK-resistant tumor cells as well as syngeneic macrophages (M phi). The induction of LAK-like activity by C.
M F, Chen, H, Suzuki, S, Yano
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Radiation-Induced Inhibition of Splenocyte Locomotion and Its Protection by C. parvum
Radiation Research, 1978Normal C57/BL mice were stimulated by intraperitoneal (ip) injection of Corynebacterium parvum (CP) prior to sublethal whole-body or local (leg) irradiation.
Isac, M +5 more
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Evidence for granulocyte-mediated macrophage activation after C. parvum immunization
Cellular Immunology, 1983It has been previously demonstrated that at the peak of the peritoneal response to Corynebacterium parvum (Day 4), cytolytic macrophages can be characterized by the presence of intracellular bacteria. In the present study, the role of neutrophils in the activation of peritoneal macrophages by C. parvum was investigated.
Chapes, S K, Haskill, S
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Effect of C. parvum on intratumor immunity to the T1699 mammary adenocarcinoma.
The Journal of Immunology, 1980Abstract The mechanism of Corynebacterium parvum-induced tumor regression has been studied in the immunogenic murine T1699 adenocarcinoma model. Administration of C. parvum to animals bearing progressor tumors resulted in significant regression frequencies after both i.p. and intratumor (IT) injection.
S, Haskill, F, Ritter, S, Becker
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The occurrence of Cryptosporidium parvum and C. muris in wild rodents and insectivores in Spain
Veterinary Parasitology, 2000Five rodent and two insectivore species were investigated for Cryptosporidium at seven sites in north-eastern Spain. Of the 442 animals studied, 82 Apodemus sylvaticus, 1 A. flavicollis, 5 Mus spretus, 1 Rattus rattus, 8 Clethrionomys glareolus and 13 Crocidura russula were infected with only C. parvum. Eleven A. sylvaticus and 2 C.
J, Torres +4 more
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Effects of C. parvum on radiation response of murine tumors.
Developments in biological standardization, 1978The effects of intravenous C. parvum (CP) on the efficacy of fractionated gamma-irradiation in treating a fairly immunogenic fibrosarcoma (FSa) and a weakly immunogenic mammary carcinoma (MDAH-MCa-4) were studied in C3Hf/Bu mice. Tumors were 8 mm in diameter at the start of irradiation.
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