Results 31 to 40 of about 28,617 (205)

Gut fungi enhances immunosuppressive function of myeloid-derived suppressor cells by activating PKM2-dependent glycolysis to promote colorectal tumorigenesis

Experimental Hematology & Oncology, 2022
Background Accumulating evidence implicates that gut fungi are associated with the pathogenesis of colorectal cancer (CRC). Our previous study has revealed that Candida tropicalis (C.
Zhiyong Zhang, Yaojun Zheng, Ying Chen, Yuxin Yin, Yuxi Chen, Qianyu Chen, Yayi Hou, Sunan Shen, Mingming Lv, Tingting Wang   +9 more
doaj   +1 more source

Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples.

PLoS Pathogens, 2021
Candida tropicalis is a human pathogen that primarily infects the immunocompromised. Whereas the genome of one isolate, C. tropicalis MYA-3404, was originally sequenced in 2009, there have been no large-scale, multi-isolate studies of the genetic and ...
Caoimhe E O'Brien, João Oliveira-Pacheco, Eoin Ó Cinnéide, Max A B Haase, Chris Todd Hittinger, Thomas R Rogers, Oscar Zaragoza, Ursula Bond, Geraldine Butler   +8 more
doaj   +1 more source

Association phenothiazine and laser on growth ofC. tropicalisfluconazole-resistant [PDF]

SPIE Proceedings, 2014
Candidiasis is caused by Candida species found on the skin, gastrointestinal tract and mucous cavities of the humans and may be acute, chronic, localized or systemic. Alhough C. albicans is the species most often identified as responsible for this type of infection C. Tropicalis has been considered an emerging cause.
Rafael Araújo Gomes Júnior, Susana C. P. S. de Oliveira, Juliana S. C. Monteiro, Gustavo M. P. Santos, Fernando J. P. Sampaio, Maria F. M. Gesteira, Fátima A. A. Zanin, Aldo Brugnera, Antônio Luiz B. Pinheiro, Marcos A. Vannier-Santos   +9 more
openaire   +1 more source

Candida tropicalis-derived vitamin B3 exerts protective effects against intestinal inflammation by promoting IL-17A/IL-22-dependent epithelial barrier function

Gut Microbes
Candida tropicalis-a prevalent gut commensal fungus in healthy individuals – contributes to intestinal health and disease. However, how commensal C. tropicalis influences intestinal homeostasis and barrier function is poorly understood.
Ha T Doan, Li-Chieh Cheng, Yi-Ling Chiu, Yuan-Kai Cheng, Cheng-Chih Hsu, Yee-Chun Chen, Hsiu-Jung Lo, Hao-Sen Chiang   +7 more
doaj   +1 more source

Overexpression of efflux pump transporter genes and mutations in ERG11 pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region

Journal of Global Antimicrobial Resistance, 2020
Introduction: Fluconazole resistance in Candida tropicalis health care–associated infections is increasing. We investigated the role of efflux pump and mutations in ERG11p conferring fluconazole resistance in C. tropicalis. Materials and methods: A total
Nidhi Pandey, Muktanand Tripathi, Munesh K. Gupta, Ragini Tilak   +3 more
doaj   +1 more source

Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance

Medical Mycology Case Reports, 2016
Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common Candida species (C ...
Marine Grosset, Marie Desnos-Ollivier, Cendrine Godet, Catherine Kauffmann-Lacroix, France Cazenave-Roblot   +4 more
doaj   +1 more source

In vitro antifungal resistance profile of Candida strains isolated from Saudi women suffering from vulvovaginitis

European Journal of Medical Research, 2020
Background Vulvovaginal candidiasis (VVC) represents a universal health hazard that contributes to significant morbidity in women. Resistance of Candida to antifungal therapy has been reported as a public health problem.
Mohamed T. Yassin, Ashraf A. Mostafa, Abdulaziz A. Al-Askar, Rashad Bdeer   +3 more
doaj   +1 more source

Comparison of the action of associated antigens and associated inactivated cells of c. Albicans and c. Tropicalis fungi

Vìsnik farmacìï, 2014
Many researchers believe that the use of drugs that can stimulate protective immune responses against candidal infections, i.e. immunobiological drugs stimulating the protective function, is promising in the fight against candidiasis. The aim of this work was to compare protective and therapeutic properties of the associated antigens and the associated
Rybalkin, M. V., Filimonova, N. I., Strelnikov, L. S.   +2 more
openaire   +3 more sources

Epidemiology, risk factors, and antifungal susceptibility analysis of Candida tropicalis and non-C.tropicalis candidemia

BMC Infectious Diseases
In recent years, the incidence of Candida tropicalis bloodstream infections has been increasing annually, drawing increasing clinical attention.
Lingning Meng, Jia Li, Danwei Wang, Mei Han, Shuo Gao, Yan Zhang, Wenbo Zhu, Chang Liu   +7 more
doaj   +1 more source

Pursuing Advances in DNA Sequencing Technology to Solve a Complex Genomic Jigsaw Puzzle: The Agglutinin-Like Sequence (ALS) Genes of Candida tropicalis

Frontiers in Microbiology, 2021
The agglutinin-like sequence (ALS) gene family encodes cell-surface adhesins that interact with host and abiotic surfaces, promoting colonization by opportunistic fungal pathogens such as Candida tropicalis.
Soon-Hwan Oh, Allyson Isenhower, Rubi Rodriguez-Bobadilla, Brooke Smith, Jillian Jones, Vit Hubka, Vit Hubka, Christopher Fields, Alvaro Hernandez, Lois L. Hoyer   +9 more
doaj   +1 more source