Results 51 to 60 of about 28,617 (205)

Breakthrough Bloodstream Infections Caused by Echinocandin-Resistant Candida tropicalis: An Emerging Threat to Immunocompromised Patients with Hematological Malignancies

Journal of Fungi, 2020
Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir, Cristina Jiménez-Ortigosa, Maria N. Gamaletsou, Audrey N. Schuetz, Rosemary Soave, Koen Van Besien, Catherine B. Small, David S. Perlin, Thomas J. Walsh   +8 more
doaj   +1 more source

Sexual biofilm formation in C andida tropicalis opaque cells [PDF]

Molecular Microbiology, 2014
Summary C andida albicans and C andida tropicalis are opportunistic fungal pathogens that can transition between white and ...
Stephen K, Jones, Matthew P, Hirakawa, Richard J, Bennett   +2 more
openaire   +2 more sources

Characterization and Susceptibility Pattern of Candida Species from Various Clinical Samples in a Rural Tertiary Care Hospital

Journal of Pure and Applied Microbiology, 2023
Fungi infections are becoming more prevalent and burdensome on a global scale leading to an important concern for immunocompromised patients. Hospitals often become infected with serious, invasive Candida infections.
Aditi Pradeep Warghade, Gargi Mudey, Supriya Meshram, Swati Kombe, Dipika Shaw   +4 more
doaj   +1 more source

Research progress on the drug resistance mechanisms of Candida tropicalis and future solutions

Frontiers in Microbiology
Candida tropicalis is an important member of the non-Candida albicans species. It is closely associated with candidemia, especially common in neutropenic and critically ill patients. Drug-resistant C.
Huisheng Xiong, Rigetu Zhao, Shizhe Han, Zhilin Liu, Xin Zhang, Zelin Jia, Jiayu Cui, Yuhang Zhang, Xueli Wang   +8 more
doaj   +1 more source

Recent Increase in the Prevalence of Fluconazole-Non-susceptible Candida tropicalis Blood Isolates in Turkey: Clinical Implication of Azole-Non-susceptible and Fluconazole Tolerant Phenotypes and Genotyping

Frontiers in Microbiology, 2020
Candida tropicalis is the fourth leading cause of candidemia in Turkey. Although C. tropicalis isolates from 1997 to 2017 were characterized as fully susceptible to antifungals, the increasing global prevalence of azole-non-susceptible (ANS) C ...
Amir Arastehfar, Süleyha Hilmioğlu-Polat, Farnaz Daneshnia, Ahmed Hafez, Mohammadreza Salehi, Furkan Polat, Melike Yaşar, Nazlı Arslan, Tuğrul Hoşbul, Nevzat Ünal, Nevzat Ünal, Dilek Yeşim Metin, Şaban Gürcan, Asuman Birinci, Ayşe Nedret Koç, Weihua Pan, Macit Ilkit, David S. Perlin, Cornelia Lass-Flörl   +18 more
doaj   +1 more source

Candida Isolates From Blood and Other Normally Sterile Foci From ICU Patients: Determination of Epidemiology, Antifungal Susceptibility Profile and Evaluation of Associated Risk Factors

Frontiers in Public Health, 2021
Background: The clinical diagnosis and therapy for ICU patients with invasive candidiasis are challenged by the changes of Candida community composition and antimicrobial resistance.
Bo Wang, Xinlong He, Xinlong He, Feng Lu, Feng Lu, Yajuan Li, Yuerong Wang, Min Zhang, Ying Huang, Jinxing Xia   +9 more
doaj   +1 more source

Antifungal effect of 7-hydroxycitronellal against C. Tropicalis strains: an in vitro approach

Bioscience Journal, 2017
The fungi of the genus Candida play a relevant role in the emergence of oral infections and are increasingly more frequent the cases of infections by non-albicans strains. In light of this context and the need for new alternatives to the antimicrobial therapy, the monoterpene [7-hidroxicitronelal] (7-HO) was evaluated for its antifungal effects.
Oliveira Filho, Abrahão Alves, Fernandes de Oliveira, Heloísa Mara Batista, Soares Medeiros, Cássio Ilan, Pessôa, Hilzeth de Luna Freire, Júnior, José Pinto de Siqueira, Lima, Edeltrudes de Oliveira   +5 more
openaire   +5 more sources

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

The Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban, Alberto Martín‐Serra, Alejandro Pérez‐Ramos, Borja Figueirido   +3 more
wiley   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek, Jean‐Marc Daran, Marieke E. Klijn, Marcel A. Vieira‐Lara   +3 more
wiley   +1 more source