Monocyte C1‐inhibitor synthesis in patients with C1‐inhibitor deficiency
Abstract. Monocytes of seven out of eight patients with type 1 C1‐inhibitor (C1‐inh) deficiency (HAE) produced 40% as much C1‐inh as monocytes from normal donors (controls). In contrast, monocytes from three patients with type 2 and three patients with acquired C1‐inh deficiency produced similar amounts of Cl‐inh as controls. Recombinant γ‐interferon (
D F, Lappin +6 more
openaire +3 more sources
Effects of weak anchoring on C1 and C2 chevron structures [PDF]
We present a theoretical study of the effect of weak anchoring on the transition between C1 and C2 chevron structures in smectic C liquid crystals. We employ a continuum theory which allows for variable cone, azimuthal and layer tilt angles.
Mottram, Nigel +2 more
core +5 more sources
The role of C1, C1-inactivator and C4 in modulating immune precipitation.
To clarify the mechanism of inhibition of immune precipitation by early components of the classical pathway of complement, aggregation of 125I-BSA-rabbit-anti-BSA antibody complexes was performed in the presence of purified C1, C1-inactivator (C1-In) and C4. C1 delayed the rate of immune precipitation in a concentration dependent manner.
Schifferli, J. A. +2 more
openaire +4 more sources
Fluid-phase interaction of C1 inhibitor (C1 Inh) and the subcomponents C1r and C1s of the first component of complement, C1 [PDF]
Interactions between proenzymic or activated complement subcomponents of C1 and C1 Inh (C1 inhibitor) were analysed by sucrose-density-gradient ultracentrifugation and sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. The interaction of C1 Inh with dimeric C1r in the presence of EDTA resulted into two bimolecular complexes accounting for a ...
S, Chesne +4 more
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PI3KC3-C1-Beclin 1-C137-S-palmitoylation.pdb
In the cryo-EM structure of PI3KC3-C1(EMDB ID:EMD-6785), the sidechain of C137 in Beclin 1 points to a proximal hydrophobic groove mainly formed by F64, Y66, and I76 residues of ATG14L, and W591 residue of VPS15.
Mengmeng Zhang (1507543) +10 more
core +1 more source
A tension approach to controlling the shape of cubic spline surfaces on FVS triangulations [PDF]
We propose a parametric tensioned version of the FVS macro-element to control the shape of the composite surface and remove artificial oscillations, bumps and other undesired behaviour.
Manni, Carla, Davydov, Oleg
core +4 more sources
Infrastrutture stradali più sicure. Fase I: i criteri [PDF]
This monograph is a PIARC technical report which will be distributed on the occasion of the XXVI National PIARC Conference to be held in Rome on 27-30 October 2010.
AIPCR Comitato Tecnico C1
core +1 more source
A method for creating a class of triangular C1 finite elements [PDF]
Finite elements providing a C1 continuous interpolation are useful in the numerical solution of problems where the underlying partial differential equation is of fourth order, such as beam and plate bending and deformation of strain-gradient-dependent ...
A. Zervos +5 more
core +1 more source
Limitations of linear GHG Protocol carbon reporting in achieving circular progress [PDF]
Net Zero plans are coming with increasing urgency from governments and the corporate sector around the world. Circular Economy is recognized as an essential pathway towards Net Zero in the reduction of supply chain emissions and governments around the ...
Wynne Astrid, Kenny Rich
doaj +1 more source
Structure of the C1r–C1s interaction of the C1 complex of complement activation [PDF]
Significance C1 is a large complex that triggers the destruction of invading pathogens via lysis or by stimulation of innate and adaptive immune processes. It is composed of C1q, a protein with a bouquet-like architecture, together with a tetramer assembled from two copies each of the serine proteases C1r and C1s, which activate when ...
Jamal O. M. Almitairi +9 more
openaire +5 more sources

