Results 51 to 60 of about 595,845 (281)

Assessing extreme flood inundation and demographic exposure in climate change using large ensemble climate simulation data in the Lower Chao Phraya River Basin of Thailand

open access: yesJournal of Hydrology: Regional Studies, 2023
Study region: Lower Chao Phraya River Basin (LCPRB), Thailand. Study focus: This study aims to make a robust assessment based on a large ensemble d4PDF dataset and a flood-inundation model Inundation Model Coupling Rainfall-runoff (IMCR) for the LCPRB ...
Aakanchya Budhathoki   +2 more
doaj   +1 more source

The C1 claw device: a new instrument for C1-C2 fusion [PDF]

open access: yesEuropean Spine Journal, 2001
A new fixation device for C1-C2 fusion is presented. It consists of a claw construct for the C1 arch that is rigidly attached to C1-C2 transarticular screws to form an instrument that combines anterior and posterior fixation in the same construct. The new device was successfully applied in a case with failed C1-C2 fusion that was initially stabilized ...
S, Olerud, C, Olerud
openaire   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Effect of mutations within the coding region of C1-INH gene on protein function in families with HAE

open access: yes, 2005
C1 esterase inhibitor (C1-INH) is a serine protease inhibitor (serpin). Serpins are a superfamily of proteins that fold into a conserved structure and utilize a unique suicide substrate-like inhibitory mechanism.
M. Cicardi   +3 more
core   +2 more sources

2010 international consensus algorithm for the diagnosis, therapy and management of hereditary angioedema [PDF]

open access: yes, 2010
Background We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) and updated this as Hereditary angioedema: a current state-of-the-art ...
S. Waserman   +251 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

The empirical analysis of financial reports of companies in Croatia: Benford distribution curve as a benchmark for first digits

open access: yesCroatian Review of Economic, Business and Social Statistics, 2019
The financial numbers game is unfortunately alive and doing well. One of the forensic accounting techniques is based on Benford’s Law and is used for the detection of unusual transactions, anomalies or trends. The aim of this paper is to test whether the
Cunjak Mataković Ivana
doaj   +1 more source

Correction to: Response to: “Does ACPA-negative RA consist of subgroups related to sustained DMARD-free remission and serological markers at disease presentation” by Masi and Fleischmann

open access: yesArthritis Research & Therapy, 2020
An amendment to this paper has been published and can be accessed via the original article.
Debbie M. Boeters   +1 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

International financial support to achieve the net-zero emissions goal could help resolve equity trade-off between developing and developed countries

open access: yesCommunications Earth & Environment
Over 100 countries have announced net-zero emissions goals. Although these net-zero emissions goals may be consistent with global 2 °C climate stabilization, their impacts on equity between developing and developed regions remain poorly understood. Here,
Shinichiro Fujimori   +7 more
doaj   +1 more source

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