Results 91 to 100 of about 77,699 (297)

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

PEER REVIEWER C11

, 2016
-C11 PEER ...
HAERANI RASYID, HAERANI RASYID
core  

A Direct C11 Alkylation Strategy on the Saxitoxin Core: A Synthesis of (+)-11-Saxitoxinethanoic Acid

, 2019
The bis-guanidinium ion family of natural products are revered for their utility in the study of ion channel physiology. While many congeners have been isolated with various oxidation and sulfation patterns, only two members of this family have been ...
Chintelle K. James (7430642), Srinivas R. Paladugu (7430639), Ryan E. Looper (1345542)   +2 more
core   +1 more source

Structure of entinostat Form B, C21H20N4O3, derived using laboratory powder diffraction data and density functional techniques

Acta Crystallographica Section E: Crystallographic Communications
The crystal structure of entinostat Form B, C21H20N4O3, has been solved and refined using laboratory X-ray powder diffraction data, and optimized using density functional techniques.
James A. Kaduk, Sunil Kumar Rai
doaj   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

C11-Chirasil-Dex as chiral stationary phase in GC: enantioselective separation of cyclopropane derivatives

, 2005
Chirasil-â-Dex containing an undecamethylene spacer (C11-Chirasil-Dex) was used as chiral stationary phase (CSP) in enantioselective gas chromatography (GC). The versatility of the new stationary phase in the simultaneous enantiomeric separation of a set
Ghanem, A (15523544)
core  

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Formal Reasoning about the C11 Weak Memory Model

, 2015
This abstract introduces the C11 weak memory model, summarises known verification results, and discusses some open ...
Vafeiadis, Viktor, Viktor Vafeiadis, Vafeiadis, V.   +2 more
core   +1 more source

Towards Deductive Verification of C11 Programs with Event-B and ProB [PDF]

, 2019
This paper introduces a technique for modelling and verifying weak memory C11 programs in the Event-B framework. We build on a recently developed operational semantics for the RAR fragment of C11, which we use as a top-level abstraction.
Brijesh Dongol, Mohammadsadegh Dalvandi, Dongol, Brijesh, Dalvandi, Mohammadsadegh   +3 more
core   +1 more source