Results 211 to 220 of about 77,699 (297)

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

Chaetocin Induces Ferroptosis in Cisplatin‐Resistant Ovarian Cancer Cells Through Neddylation‐Mediated TFRC Upregulation

Phytotherapy Research, EarlyView.
Chaetocin induces ferroptosis in cisplatin‐resistant ovarian cancer cells through neddylation‐mediated TFRC upregulation. ABSTRACT Ovarian cancer (OV) is a highly lethal gynecological tumor, often developing platinum chemotherapy resistance and treatment failure.
Hanfei Xie, Wumin Dai, Lu Sun, Wangang Gong, Tao Zhu, Yingli Zhang   +5 more
wiley   +1 more source

<i>N</i>,<i>N</i>'-Bis(2,6-diiso-propyl-phen-yl)-<i>N</i>-hy-droxy-formamidine-<i>N</i>,<i>N</i>'-bis-(2,6-diiso-propyl-phen-yl)-<i>N</i>-oxidoformamidinium (1/1). [PDF]

IUCrdata
Juma DO, Adeleke AA, Zamisa SJ, Omondi B, Bongoza U, Njogu EM.   +5 more
europepmc   +1 more source

Neohesperidin Alleviates Ferroptosis in Doxorubicin‐Induced Cardiotoxicity via Mettl3‐m6A‐Nrf2 Signaling

Phytotherapy Research, EarlyView.
Neohesperidin alleviates doxorubicin‐induced cardiotoxicity by inhibiting METTL3‐mediated m6A modification of Nrf2 mRNA, thereby regulating Nrf2 and suppressing ferroptosis. ABSTRACT Doxorubicin (DOX) has antitumor efficacy, but its clinical application is restricted by multiple side effects, especially cardiotoxicity.
Ruijia Wen, Xin Dong, Haowen Zhuang, Yusheng Huang, Mengyuan Wang, Zhongzheng Zhang, Jinhong Chen, Wei Wang, Chun Li, Junyan Wang   +9 more
wiley   +1 more source

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

Phytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng, Xuelian Yuan, Yawen Xie, Zhenni Xia, Zhaohui Guo, Xuesong Liu, Rong Li, Wenliang Wang   +7 more
wiley   +1 more source

Gradient‐ and Newton‐Based Unit Vector Extremum Seeking Control

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This paper proposes new methods for stable and efficient convergence in multivariable extremum seeking control (ESC) using sliding mode techniques. Inspired by classical sliding modes and finite‐time control, the approach integrates these ideas into gradient‐ and Newton‐based ESC schemes with sinusoidal perturbations.
Roberto Luo, Victor Hugo Pereira Rodrigues, Tiago Roux Oliveira, Miroslav Krstic   +3 more
wiley   +1 more source

Synthesis and crystal structures of three silicon complexes with <i>N</i>-[(2-hy-droxy-naphthalen-1-yl)methyl-idene]alanine. [PDF]

Acta Crystallogr E Crystallogr Commun
Schwarzer A, Fels S, Böhme U.
europepmc   +1 more source