Results 141 to 150 of about 219,049 (307)

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

The FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna, Christoff Odendaal, Madhulika Singh, Albert Gerding, Miriam Langelaar‐Makkinje, Marianne van der Zwaag, Asmara Drachman, Vladimíra Cetkovská, Gaby Liem Foeng Kioen, Anne‐Claire M. F. Martines, Nicolette C. A. Huijkman, Hein Schepers, Bart van de Sluis, Dirk‐Jan Reijngoud, Ody C. M. Sibon, Amy C. Harms, Thomas Hankemeier, Barbara M. Bakker   +17 more
wiley   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

Minimalist, bioinspired and sensorial emulsion based on a Ca2+ double cone vector system using Design of Experiment (DoE)

International Journal of Cosmetic Science, EarlyView.
Development of a biomimetic calcium‐based minimalist skin formulation using Design of Experiment (DoE) to correlate key ingredients' effect on the sensory and physico‐chemical properties of the emulsion. Abstract Objectives Innovation is considered a determining factor in the highly competitive environment of the cosmetic industry to introduce products
Marc Lavarde, Marjorie Lassalle, Solène Gouot, Ysaline Corroyer, Clara Marceau, Vincent Briffaut, Stéphane Poigny, Samar Issa   +7 more
wiley   +1 more source

Fungicidal activity of truncated analogues of dihydrosphingosine [PDF]

, 2008
Cammue, Bruno PA, Chow, Kuen K, François, Isabelle EJA, Hillaert, Ulrik, Meert, Els MK, Thevissen, Karin, Van Calenbergh, Serge   +6 more
core   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

Journal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang, Jingying Li, Yucai Li, Lei Yan, Christina Seok Yien Yong, Shaoya Li, Yubing He, Lanqin Xia   +7 more
wiley   +1 more source

Conférences (C1 – C15) [PDF]

médecine/sciences, 2010
openaire   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

The Core‐Periphery Model Under Additively Separable Preferences

Journal of Regional Science, Volume 65, Issue 2, Page 378-402, March 2025.
ABSTRACT This paper reexamines Krugman's core‐periphery model by substituting his constant elasticity of substitution (CES) utility with a general additively separable utility that comprehensively captures the pro‐competitive effect while preserving the income effect.
Congcong Wang, Dao‐Zhi Zeng, Xiwei Zhu
wiley   +1 more source

Estimating National and Foreign Trade Elasticities Using Generalized Transport Costs

Journal of Regional Science, Volume 65, Issue 2, Page 471-496, March 2025.
ABSTRACT We introduce the definition of two distinct trade elasticities corresponding to imports from regions located in the same country (national elasticities) and foreign regions located in other countries (foreign elasticities). We resort to a three‐tier nested CES utility structure to derive the corresponding demand gravity equations.
José L. Zofío, Jorge Díaz‐Lanchas, Damiaan Persyn, Javier Barbero   +3 more
wiley   +1 more source

The algal homolog of the plant CER1 and CER3 proteins is a bifunctional hydrocarbon‐forming enzyme

New Phytologist, EarlyView.
Schematic representation of the proposed reactions carried out by a CER1/3 protein from green algae. CoA, coenzyme A; CTD, C‐terminal domain; Cys, catalytic cysteine of C‐terminal domain; His, catalytic histidines of N‐terminal domain; NTD, N‐terminal domain.
Ángel Baca‐Porcel, Bertrand Légeret, Alexandre Six, Mallaury Cabanel, Mathilde Le Cossec, Arthur Guegano, Damien Sorigué, Yonghua Li‐Beisson, Florian Veillet, Fred Beisson   +9 more
wiley   +1 more source