Results 241 to 250 of about 571,919 (313)

Crystal structure of (dibenzo-21-crown-7)di-iodido-samarium(II) 1,2-di-meth-oxy-ethane hemisolvate. [PDF]

Acta Crystallogr E Crystallogr Commun
Wineinger HB, Sperling JM, Albrecht TE.
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Milk Fatty Acid Profile and Production Traits in Lithuanian Local and Holstein Cattle Breeds. [PDF]

Animals (Basel)
Mišeikienė R, Tušas S, Bartkienė E, Šarkauskienė J, Matusevičius P.   +4 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Propionic Acid Outperforms Formic and Acetic Acid in MS Sensitivity for High-Flow Reversed-Phase LC-MS Bottom-Up Proteomics. [PDF]

Anal Chem
Starovoit MR, Jadeja S, Kupčík R, Vatić S, Rasl J, Demir D, Novák P, Braswell C, Orsburn BC, Lenčo J.   +9 more
europepmc   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Enhanced synthesis of 1, 3-medium chain-2-long chain triacylglycerols by engineered Saccharomyces cerevisiae. [PDF]

Bioresour Bioprocess
Peng Z, Zhang Z, Gao R, Deng L, Wang F, Liu J.   +5 more
europepmc   +1 more source

C18-C22 monounsaturated FA samples

These fractions are obtained as a result of the oil enrichment through short path distillation, cold precipitation, molecular distillation, and other separation technologies as SFE/SCE or bio-enzymatical techniques. After this enrichment and apart from the monounsaturated fractions, PUFAS will be also obtained, which will be subsequently fractionated ...
openaire   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Crystal structure of (1<i>Z</i>,2<i>Z</i>)-<i>N</i> ¹,<i>N</i> ²-diisobutyl-1,2-di-phenyl-ethane-1,2-di-imine. [PDF]

Acta Crystallogr E Crystallogr Commun
Eltayeb NE, Lasri J, Almehmadi YA, Hökelek T, McKay AP.   +4 more
europepmc   +1 more source