A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Synthesis, crystal structure and Hirshfeld surface analysis of bis-(2-amino-1,3,4-thia-diazol-3-ium) diaqua-dichlorido(propanedioato-κ<sup>2</sup> <i>O</i> <sup>1</sup>,<i>O</i> <sup>3</sup>)manganate(II). [PDF]
Nuralieva G +6 more
europepmc +1 more source
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz +11 more
wiley +1 more source
Synthesis and crystal structure of ethyl 2-(1,3-benzo-thia-zol-2-yl)-1-oxo-1<i>H</i>-pyrido[2,1-<i>b</i>][1,3]benzo-thia-zole-4-carboxyl-ate. [PDF]
Elboshi HA +3 more
europepmc +1 more source
Scheme illustrating the selective conversion of plastic waste to isomerized C4‐C12 products using RuSZ1 under different reaction conditions. ABSTRACT In recent years, catalytic hydrocracking has emerged as a promising waste‐to‐feedstock solution for processing plastic waste.
Xinbang Wu +8 more
wiley +1 more source
Syntheses and structures of bis(2-amino-py-rimi-dine-κ<i>N</i> <sup>1</sup>)di-chlorido-zinc(II) (ortho-rhom-bic polymorph) and bis(2-am-ino-py-rimi-dine-κ<i>N</i> <sup>1</sup>)di-iodido-zinc(II). [PDF]
Näther C, Bhosekar G.
europepmc +1 more source
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang +6 more
wiley +1 more source
C2 Slope as an Independent Predictor of Cervical Lordosis Loss Following Laminoplasty. [PDF]
Zheng B, Yu P, Zhu Z, Liang Y, Liu H.
europepmc +1 more source
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu +8 more
wiley +1 more source
Fusobacterium nucleatum manipulates host autophagy to promote its intracellular survival and treatment resistance in nasopharyngeal carcinoma. [PDF]
Wang JY +15 more
europepmc +1 more source

