Results 181 to 190 of about 104,486 (292)

Loss of p62 Binding Allows TIF‐IA Accumulation in Senescence, Which Promotes Phenotypic Changes to Nucleoli and the Senescence Associated Secretory Phenotype

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
P62‐TIF‐IA–mediated regulation of senescence and ageing. In healthy tissue, p62 facilitates TIF‐IA turnover. Upon senescence induction, ATM activation increases TIF‐IA phosphorylation at S44, reducing its p62 binding and causing TIF‐IA accumulation.
Hazel C. Thoms   +17 more
wiley   +1 more source

Consistent supra-molecular motif of <i>C</i>(7) O-H⋯O hydrogen-bonded chains and different local symmetries in three iso-indole-4-carb-oxy-lic acid derivatives. [PDF]

open access: yesActa Crystallogr E Crystallogr Commun
Alekseeva KA   +5 more
europepmc   +1 more source

Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 475-491, January 2026.
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory   +3 more
wiley   +1 more source

Bis{2-[bis-(2-hy-droxy-eth-yl)amino]-acetato}-zinc(II) monohydrate. [PDF]

open access: yesIUCrdata
Rakovský E   +4 more
europepmc   +1 more source

Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress [PDF]

open access: bronze, 2009
Bimei Jiang   +7 more
openalex   +1 more source

Effect of remnant cholesterol on the onset of diabetes mellitus

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 1, Page 120-128, January 2026.
Higher Rem‐C was a risk factor for DM onset in the younger population (under 50 years old) in both sexes. Other factors such as FPG and BMI were stronger risk factors than Rem‐C for diabetes development in individuals over 50 years of age. To effectively reduce the incidence of DM, it is necessary to focus on different factors depending on the age ...
Teruki Miyake   +21 more
wiley   +1 more source

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