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Marine-Derived Macrolides 1990–2020: An Overview of Chemical and Biological Diversity
Marine Drugs, 2021 Macrolides are a significant family of natural products with diverse structures and bioactivities. Considerable effort has been made in recent decades to isolate additional macrolides and characterize their chemical and bioactive properties. The majority
Hairong Zhang +7 more
exaly +3 more sources
Long-Term Macrolides in Chronic Respiratory Diseases: Dusk or a New Dawn? A Narrative Review [PDF]
AntibioticsMacrolides—especially azithromycin—have been increasingly investigated in chronic respiratory diseases for their combined antimicrobial, anti-inflammatory, and immunomodulatory properties.
Daniele Previtero +9 more
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Understanding the evolution of macrolides resistance: A mini review
Journal of Global Antimicrobial ResistanceBackground: Macrolides inhibit the growth of bacterial cells by preventing the elongation of polypeptides during protein biosynthesis and include natural, synthetic, and semi-synthetic products. Elongation prevention occurs by blocking the passage of the
Rohaidah H, Nur Asyura Binti Nor Amdan
exaly +3 more sources
Macrolides: From Toxins to Therapeutics
Toxins, 2021 Macrolides are a diverse class of hydrophobic compounds characterized by a macrocyclic lactone ring and distinguished by variable side chains/groups. Some of the most well characterized macrolides are toxins produced by marine bacteria, sea sponges, and ...
Kiersten D. Lenz +3 more
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Prevalence and Antibiotic Susceptibility Patterns of Mycoplasma Hominis and Ureaplasma Urealyticum in Females with Genital Infections from Central Kerala, India [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Genital mycoplasmas namely Mycoplasma Hominis and Ureaplasma Urealyticum are sexually transmitted disease pathogens which are associated with genital infections, infertility, obstetric and neonatal complications.
SNEHA RAJAN, Suryakala R Nair
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Macrolides Decrease the Proinflammatory Activity of Macrolide-Resistant Streptococcus pneumoniae
Microbiology Spectrum, 2023 Over the past 2 decades, the prevalence of macrolide-resistant Streptococcus pneumoniae (MRSP) has increased considerably, due to widespread macrolide use.
Hisanori Domon +7 more
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Macrolides and pneumonia [PDF]
Thorax, 2013 Community acquired pneumonia (CAP) is increasing in incidence, and is presently responsible for about 1% of emergency medical admissions with an associated mortality of between 5% and 24%. Improving the outcome of CAP is, therefore, a major health priority, but what is the best method to do this?
Jeremy Stuart, Brown, Adam T, Hill
openaire +2 more sources
Immunomodulation of endothelial cells induced by macrolide therapy in a model of septic stimulation
Immunity, Inflammation and Disease, 2021 Objectives Sepsis is defined as the host's inflammatory response to a life‐threatening infection. The endothelium is implicated in immunoregulation during sepsis. Macrolides have been proposed to display immunomodulatory properties.
Stéphanie Pons +9 more
doaj +1 more source
Microbiology Spectrum, 2021 Mycoplasma bovis causes many health and welfare problems in cattle. Due to the absence of clear insights regarding transmission dynamics and the lack of a registered vaccine in Europe, control of an outbreak depends mainly on antimicrobial therapy ...
Jade Bokma +6 more
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