Macrolides: a promising pharmacologic therapy for chronic obstructive pulmonary disease
Therapeutic Advances in Respiratory Disease, 2017 Chronic inflammation plays a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, there are no effective anti-inflammatory pharmacologic therapies available for COPD so far.
Shilin Qiu, Xiaoning Zhong
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The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study [PDF]
, 2009 PhDBackground The mechanisms of the rhinitic process are complex. Previous studies upon nasal epithelial cells have begun to investigate rhinitis.
Kuchai, Romana
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Macrolides from rare actinomycetes:Structures and bioactivities [PDF]
, 2022 Rare actinomycetes are a source of numerous diverse, biologically active secondary metabolites, including macrolides, which have been shown to display several antibiotic activities.
Threadgill, Michael D. +7 more
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, 2022 Archive of macrolides containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875) +5 more
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Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro) [PDF]
, 2023 SARS-CoV-2, the new coronavirus variant is a world-wide health crisis. Over spans of human history, preparations derived from natural products have always been recognized as a preliminary source of medications.
Florbela , Pereira +8 more
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Macrolides et pneumopathies chroniques [Macrolides antibiotics and chronic pulmonary disease]
, 2022 Macrolides are commonly used antibiotics due to their broad spectrum of activity and good bioavailability. More recently, they have been shown to be effective in certain chronic lung diseases by reducing exacerbation frequency.
Von Garnier, C., Mouraux, S., Nater, A.
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Macrolides versus placebo for chronic asthma. [PDF]
, 2021 BACKGROUND: Asthma is a chronic disease in which inflammation of the airways causes symptomatic wheezing, coughing and difficult breathing. Macrolides are antibiotics with antimicrobial and anti-inflammatory activities that have been explored for the ...
Giovanni Ferrara +15 more
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Proportion of prescribed macrolides among all macrolides as a function of age during 2013–2018.
, 2023 Proportion of prescribed macrolides among all macrolides as a function of age during 2013–2018.
Satoshi Ide (3498026) +9 more
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The Renaissance of Spiramycin in Clinical Practice
Антибиотики и Химиотерапия, 2023 Spiramycin is a natural 16-membered macrolide antibiotic that has been used in clinical practice for about 70 years. Despite long-term use, spiramycin retains its position in clinical practice; the resistance of the main respiratory and urogenital ...
S. V. Yakovlev, М. Р. Suvorova
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Placing Ureaplasma within the Context of Bronchopulmonary Dysplasia Endotypes and Phenotypes
Children, 2023 Different pathophysiological pathways (endotypes), leading to very preterm birth may result in distinct clinical phenotypes of bronchopulmonary dysplasia (BPD). Ureaplasma is a unique player in the pathogenesis of BPD.
Karen Van Mechelen +4 more
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