Results 21 to 30 of about 54,415 (288)
Macrolides: a promising pharmacologic therapy for chronic obstructive pulmonary disease
Therapeutic Advances in Respiratory Disease, 2017 Chronic inflammation plays a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, there are no effective anti-inflammatory pharmacologic therapies available for COPD so far.
Shilin Qiu, Xiaoning Zhong
doaj +1 more source
Community-acquired pneumonia: antibiotic therapy approach after the COVID-19 pandemic. A review
Consilium Medicum, 2023 Pneumonia is clearly differentiated from other focal inflammatory lung diseases of non-infectious origin. A patient with community-acquired pneumonia (CAP) should receive antibacterial drugs no later than 4 hours after the diagnosis.
Andrey A. Zaytsev, Igor A. Guchev
doaj +1 more source
From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials
Antibiotics, 2016 Macrolides, as a class of natural or semisynthetic products, express their antibacterial activity primarily by reversible binding to the bacterial 50S ribosomal subunits and by blocking nascent proteins’ progression through their exit tunnel in bacterial
Dubravko Jelić, Roberto Antolović
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CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Tulathromycin – a semi-synthetic macrolidе antibiotic. I. Characteristics and antibacterial activity
Bulgarian Journal of Veterinary Medicine, 2023 This article reviews the available literature on the characteristics and antimicrobial activity of the semi-synthetic macrolide antibiotic tulathromycin from the triamilides subclass.
D. Mladenov, S. Yordanov, A. Dimitrova
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Microorganisms, 2022 Mycoplasma genitalium causes sexually transmitted infecti.ons in men and women. Treatment failures to macrolides and fluoroquinolones have been reported worldwide. Although the mgpB typing method has often been used in M. genitalium-infected men who have
Jennifer Guiraud +5 more
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Macrolide and macrolide-related antibacterial agents
Folia Pharmacologica Japonica, 2007 マクロライド系抗菌薬は，グラム陽性菌および非定型病原体に対する抗菌力が強く，呼吸器疾患の治療薬として汎用されてきた．我が国では，14員環，15員環および16員環マクロライド系およびケトライド系抗菌薬が上市している．エリスロマイシンの欠点を克服するための創薬研究から，ニューマクロライドと呼ばれるマクロライド系抗菌薬のロキシスロマイシン，クラリスロマイシンおよびアジスロマイシンが半合成された．その後，耐性肺炎球菌に対する抗菌活性が増強された，ケトライド系抗菌薬のテリスロマイシンが半合成された．本稿では主として，14，15員環マクロライド系およびケトライド系を中心とした抗菌薬の創薬・開発研究の歴史ならびに抗菌作用の特徴を概説した．
openaire +3 more sources
A systematic review and meta-analysis of macrolides in the management of adult patients with asthma
Allergology InternationalBackground: The efficacy of macrolides in the management of asthma has been studied but remains controversial. We conducted a systematic review and meta-analysis of macrolides in the management of adult patients with asthma.
Hiroshi Ohnishi +5 more
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Macrolides and COVID-19: An optimum premise
Biomedical and Biotechnology Research Journal, 2020 The epidemic of coronavirus infection disease 19 (COVID-19), which started in Wuhan City, is caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) which binds angiotensin-converting enzyme 2 (ACE2) receptor, which is highly expressed by ...
Hayder M Al-Kuraishy +3 more
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Does Azithromycin and Cetirizine Combination Given for Upper Respiratory Tract Infections has any Significant Effect on QTc? [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Azithromycin usage in patients with baseline cardiovascular risk is associated with increased risk of cardiovascular mortality, following which Food and Drug Administration (FDA) issued a black box warning regarding safety of ...
Kishor Kumar Rajasekaran +2 more
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