Potentiation of antimicrobial activity of colistin with antibiotics of different groups against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa [PDF]
Objective. To reveal antibiotics being capable of potentiating the antimicrobial activity of colistin against multidrug- and extensively drug-resistant strains of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa. Materials and
Tapalskiy D.V. +3 more
doaj +1 more source
Purpose: Inflammatory myofibroblastic tumors (IMTs) are rare, benign lesions most often seen in the lung of young adults but can occur in children, in various sites.
Mohamad Hussain Mir +4 more
doaj +1 more source
Marine Macrolides to Tackle Antimicrobial Resistance of Mycobacterium tuberculosis [PDF]
Tuberculosis has become a major health problem globally. This is worsened by the emergence of resistant strains of Mycobacterium tuberculosis showing ability to evade the effectiveness of the current antimycobacterial therapies.
Nainu, Firzan +20 more
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Macrolide Therapy in Respiratory Viral Infections
Background. Macrolides have received considerable attention for their anti-inflammatory and immunomodulatory actions beyond the antibacterial effect. These two properties may ensure some efficacy in a wide spectrum of respiratory viral infections.
Jin-Young Min, Yong Ju Jang
doaj +1 more source
Familial Occurrence of Mycoplasma-induced Rash and Mucositis: A Case Report of Two Siblings [PDF]
Mycoplasma pneumoniae is a common pathogen responsible for respiratory infections, including community-acquired pneumonia, and up to 25% of patients develop extrapulmonary complications.
Roja Aepala +4 more
doaj +1 more source
Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
wiley +2 more sources
Persistence of Resistant Staphylococcus epidermidis after Single Course of Clarithromycin
We examined how a common therapy that includes clarithromycin affects normally colonizing Staphylococcus epidermidis. Samples from the nostrils of 5 patients receiving therapy were collected before, immediately after, 1 year after, and 4 years after ...
Maria Sjölund +4 more
doaj +1 more source
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji +5 more
wiley +2 more sources
Community-acquired pneumonia: antibiotic therapy approach after the COVID-19 pandemic. A review
Pneumonia is clearly differentiated from other focal inflammatory lung diseases of non-infectious origin. A patient with community-acquired pneumonia (CAP) should receive antibacterial drugs no later than 4 hours after the diagnosis.
Andrey A. Zaytsev, Igor A. Guchev
doaj +1 more source

