Results 41 to 50 of about 2,856,075 (328)

C3 glomerulopathies: dense deposit disease and C3 glomerulonephritis

Frontiers in Medicine, 2023
Dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) are types of membranoproliferative glomerulonephritis classified as C3 glomerulopathies. These conditions are characterized by an increased number of intraglomerular cells and diffuse thickening of the glomerular capillary walls, along with the deposition of C3 and minimal or absent ...
Claudio Ponticelli, Marta Calatroni, Marta Calatroni, Gabriella Moroni, Gabriella Moroni   +4 more
openaire   +3 more sources

THE IMPORTANCE OF GLOMERULAR C3 ACCUMULATION IN ELDERLY PATIENTS WITH PRIMARY MEMBRANOUS NEPHROPATHY

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: The purpose of this study was to investigate the impact of glomerular C3 accumulation density on clinical, histopathological parameters and outcomes in elderly (>60 years) individuals with primary membranous nephropathy (PMN).
Özgür Akın Oto, Şafak Mirioğlu, Ahmet Burak Dirim, Seda Şafak, Nurana Güller, Erol Demir, Ayşe Serra Artan, Mesude Yasemin Özlük, Ali Rıza Uçar, Lala Soltanova, Kanan Nuriyev, Halil Yazıcı, Yaşar Kerem Çalışkan   +12 more
doaj   +1 more source

Tars: Timeliness-aware Adaptive Replica Selection for Key-Value Stores

, 2017
In current large-scale distributed key-value stores, a single end-user request may lead to key-value access across tens or hundreds of servers. The tail latency of these key-value accesses is crucial to the user experience and greatly impacts the revenue.
Fang, Liyuan, Jiang, Wanchun, Wang, Jianxin, Xie, Haiming, Zhou, Xiangqian   +4 more
core   +1 more source

Increased C3 productivity in Midwestern lawns since 1982 revealed by carbon isotopes in Amanita thiersii [PDF]

, 2017
How climate and rising carbon dioxide concentrations (pCO2) have influenced competition between C3 and C4 plants over the last 50 years is a critical uncertainty in climate change research.
Craine, Joseph M., Hobbie, Erik A., Linder, Ernst, Pringle, Anne, Schubert, Brian A.   +4 more
core   +2 more sources

Effect of the boundary condition on the vortex patterns in mesoscopic three-dimensional superconductors - disk and sphere [PDF]

, 2007
The vortex state of mesoscopic three-dimensional superconductors is determined using a minimization procedure of the Ginzburg-Landau free energy.
Antonio R. de C. Romaguera, F. M. Peeters, G. S. Mkrtchyan, M. M. Doria, Mauro M. Doria, O. Buisson   +5 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

An Investigation of Some Immunological and Hematological Variables in Women with Systemic Lupus Erythematosus

Medical Journal of Babylon
Background:The autoimmune disease systemic lupus erythematosus (SLE) can cause multisystemic tissue damage because of the interaction between the autoantibodies and self-antigens.
Hawraa S. Al-Mozani, Sajidah F. Hasan
doaj   +1 more source

Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]

, 2019
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone, Chimenti, Paola, Cirilli, Roberto, Guglielmi, Paolo, Petzer, Anél, Petzer, Jacobus P., Poli, Giulio, Rotondi, Giulia, Secci, Daniela   +8 more
core   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A SINGLE CENTRE EXPERIENCE OF LOW C3/C4 LEVELS AND OTHER LABORATORY ASPECTS IN TURKISH CHILDREN WITH IMMUNOGLOBULIN A VASCULITIS

Sabiad
Objective: Immunoglobulin A vasculitis (IgAV) is the most prevalent systemic vasculitis in childhood. This intricate immune-mediated vasculitis affects the small blood vessels in several organ systems.
Şeyda Doğantan, Sema Nur Taşkın
doaj   +1 more source