Results 181 to 190 of about 395,454 (285)

Beyond the Index Case: A Practical Framework for Cascade Family Screening in Hereditary Angioedema. [PDF]

Clin Rev Allergy Immunol
Leung GK, Kan AK, Li PH.
europepmc   +1 more source

M%c4%b0MARLIK%2fYAPI%20B%c4%b0LG%c4%b0S%c4%b0%20ALANINDA%20YAPILAN%20DOKTORA%20TEZLER%c4%b0N%c4%b0N%20ANAL%c4%b0Z%c4%b0%20

International Journal of Social Humanities Sciences Research (JSHSR), 2018
openaire   +1 more source

LLMs as Representation Generators for Gradient‐Free Scientific Optimization: A Case Study in Battery Fast Charging

Advanced Science, EarlyView.
Large language models serve as representation generators for gradient‐free scientific optimization. Two complementary approaches produce executable battery‐charging policies either directly or through LLM‐designed neural representations coupled to Bayesian optimization.
Ge Lei, Ferran Brosa Planella, Sterling G. Baird, Samuel J. Cooper   +3 more
wiley   +1 more source

Aurora kinase a phosphorylates and stabilizes UHRF1 to maintain DNA methylation and prostate cancer cell survival. [PDF]

Epigenetics
Xiang Q, Peng Y, Ye Y, Li X.
europepmc   +1 more source

DUYGUSAL%20ZEKA%20%c4%b0LE%20G%c4%b0R%c4%b0%c5%9e%c4%b0MC%c4%b0L%c4%b0K%20E%c4%9e%c4%b0L%c4%b0M%c4%b0%20%c4%b0L%c4%b0%c5%9eK%c4%b0S%c4%b0%3a%20DEGA%20KATILIMCILARI%20%c3%9cZER%c4%b0NE%20B%c4%b0R%20ARA%c5%9eTIRMA

International Journal of Social Humanities Sciences Research (JSHSR), 2018
openaire   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

α-l-Glucose. [PDF]

IUCrdata
Takashita T, Horii Y, Ishii T.
europepmc   +1 more source

Non‐Covalent Reversibly Photoconvertible Fluorescent Tags for Wash‐Free Protein Labeling

Advanced Science, EarlyView.
FAST proteins combined with one or two fluorogens undergo reversible fluorescence switching or photoconversion through photoisomerization. At low fluorogen concentration and high light intensity, they act as negative or positive photoswitchers and photoconvertible tags, which are promising for discriminating FAST variants.
Mrinal Mandal, Yuriy Shpinov, Aliénor Lahlou, Fivos Pham, Lina El Hajji, Ian Coghill, Eve Laureau, Marie‐Aude Plamont, Franck Perez, Thomas Le Saux, Isabelle Aujard, Arnaud Gautier, Ludovic Jullien   +12 more
wiley   +1 more source

L%c4%b0SANS%20D%c3%9cZEY%c4%b0NDE%20MUHASEBE%20E%c4%9e%c4%b0T%c4%b0M%c4%b0%20ALAN%20%c3%96%c4%9eRENC%c4%b0LER%c4%b0N%20MESLEK%20ET%c4%b0%c4%9e%c4%b0%20ALGILARINDA%20ETK%c4%b0L%c4%b0%20OLAN%20FAKT%c3%96RLER%c4%b0N%20ARA%c5%9eTIRILMASI

International Journal of Social Humanities Sciences Research (JSHSR), 2018
openaire   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

Advanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu, Jiachen Wang, Chunmeng Ding, Changfa Xia, Yunyong Liu, Yuanjie Zheng, Sheng Chang, Shaokai Zhang, Yutong He, Ruifang Sun, Yunfeng Xi, Yan Liu, Kun Qian, Wanqing Chen   +13 more
wiley   +1 more source