Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cercospora leaf spot of olive (CLSO), caused by Pseudocercospora cladosporioides, is one of the most important foliar diseases of olives worldwide. This study aimed to evaluate the effect of a wide range of fungicides on mycelial growth and conidial ...
Joaquín Romero +4 more
doaj +1 more source
REVERSE ENGINEERING AND 3D MODELLING FOR DIGITAL DOCUMENTATION OF MARITIME HERITAGE [PDF]
heritage in general. Despite this has been stressed with emphasis, three dimensional modelling of maritime cultural heritage is still not usual as for archaeology and architecture.
F. Menna, E. Nocerino, A. Scamardella
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Oxygen Requirement and Inhibition of C4 Photosynthesis . An Analysis of C4 Plants Deficient in the C3 and C4 Cycles [PDF]
The basis for O2 sensitivity of C4 photosynthesis was evaluated using a C4-cycle-limited mutant of Amaranthus edulis (a phosphoenolpyruvate carboxylase-deficient mutant), and a C3-cycle-limited transformant of Flaveria bidentis (an antisense ribulose-1,5-
Dever, L.V. +6 more
core +1 more source
Spatial and temporal variablity of nonmethane hydrocarbon mixing ratios and their relation to photochemical lifetime [PDF]
The relationship between temporal and spatial variability of C2-C8 nonmethane hydrocarbon mixing ratios and their HO lifetimes (τ) is presented for samples collected during the 1993 North Atlantic Regional Experiment (NARE) and from other urban and ...
Blake, DR +7 more
core +2 more sources
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source
Congener-Specific Numbering Systems for the Environmentally Relevant C4 through C8 Perfluorinated Homologue Groups of Alkyl Sulfonates, Carboxylates, Telomer Alcohols and Acids, and Their Derivatives [PDF]
We introduce a congener-specific numbering system for the C4 through C8 perfluorinated homologue groups of alkyl sulfonates, carboxylates, telomer alcohols and acids, and their derivatives.
Kaya Forest +3 more
core +3 more sources
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE), but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung +6 more
wiley +1 more source
Alternative Splicing of Circadian Clock Genes Correlates With Temperature in Field-Grown Sugarcane [PDF]
Alternative Splicing (AS) is a mechanism that generates different mature transcripts from precursor mRNAs (pre-mRNAs) of the same gene. In plants, a wide range of physiological and metabolic events are related to AS, as well as fast responses to changes ...
Alabadí +111 more
core +2 more sources

