Results 51 to 60 of about 7,330 (174)
Advanced Science, Volume 13, Issue 53, 24 September 2026.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
, 2023 RA acknowledges funding from the EU H2020 program “Graphene Flagship” (Grant Agreement 881603) and EU H2020 program “ESTEEM3” (Grant Agreement 823717).
Simon Hettler +9 more
core +1 more source
Archiv der Pharmazie, Volume 359, Issue 9, September 2026.We screened acrylamide bioisosteres against KRasG12C and prioritized primary hits by their GSH reactivity, labeling efficiency and specificity. The most promising fragment was combined with a KRas‐binding scaffold. Covalent binding, inhibitory activity and selectivity were confirmed via MS, NMR, biochemical and cell viability assays.
Nikolett Péczka +11 more
wiley +1 more source
The Prostate, Volume 86, Issue 13, Page 1332-1340, September 15, 2026.ABSTRACT Background Benign prostatic hyperplasia (BPH) leads to prostate enlargement and lower urinary tract symptoms that can resist treatment. A histologic hallmark of BPH is glandular epithelial hyperplasia with new ductal branching morphogenesis. The stromal inductive factors driving tissue morphogenesis may provide new therapeutic targets, but are
Anna S. Pollack +2 more
wiley +1 more source
Overexpression of Murine Rnaset2 in a Colon Syngeneic Mouse Carcinoma Model Leads to Rebalance of Intra-Tumor M1/M2 Macrophage Ratio, Activation of T Cells, Delayed Tumor Growth, and Rejection [PDF]
, 2020 Human RNASET2 acts as a powerful oncosuppressor protein in in vivo xenograft-based murine models of human cancer. Secretion of RNASET2 in the tumor microenvironment seems involved in tumor suppression, following recruitment of M1-polarizedmacrophages ...
Lorenzo Mortara +8 more
core +1 more source
International Journal of Cancer, Volume 159, Issue 4, Page 844-852, 15 August 2026.What's new? Cancers of the breast and female genital tract represent more than half of all cancers in women in sub‐Saharan Africa. Here, the authors assessed incidence trends in a female population living in urban sub‐Saharan Africa based on the Zimbabwe National Cancer Registry in Harare over a 30‐year period.
Eric Chokunonga +7 more
wiley +1 more source
Nationwide Study on the Cervical Cancer Screening Pathway in Estonia
International Journal of Cancer, Volume 159, Issue 4, Page 883-895, 15 August 2026.Cervical cancer remains a significant burden despite being preventable, largely due to inadequate screening participation and poor follow‐up of high‐risk women. Here, the authors investigated follow‐up rates among women who tested positive for high‐risk human papillomavirus (hr‐HPV) infection in primary screening in Estonia. Data show that more than 57
Aleksandra Šavrova +6 more
wiley +1 more source
, 2017 Monoclonal antibody (mAb) therapy represents an attractive targeted approach for the treatment of cancer. Nevertheless, only a limited number of antigens on solid tumours have been exploited. To address the diverse clinical spectrum of ovarian and breast
Cua, Simeon
core +1 more source
Journal of Economics and Management, 2019 Aim/purpose – General real estate taxation is a process regulated, inter alia, by the Real Estate Management Act. It is intended to establish a tax base for real estate in the event of a change in real estate tax base.
Gnat Sebastian
doaj +1 more source
Cortisol Recognition by a Conformationally Responsive DNA Aptamer
Advanced Sensor Research, Volume 5, Issue 8, August 2026.The full‐length 85mer cortisol aptamer intrinsically populates two metastable conformational states in equilibrium. Cortisol binding redistributes the conformational ensemble by shifting the equilibrium between open and compact states while maintaining the underlying secondary structure. This ligand‐induced tertiary reorganization provides an atomistic
Lakshitha Jasin Arachchige +4 more
wiley +1 more source