Results 1 to 10 of about 7,139 (200)

Transcriptome analysis identifies an ASD-Like phenotype in oligodendrocytes and microglia from C58/J amygdala that is dependent on sex and sociability [PDF]

Behavioral and Brain Functions
Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with higher incidence in males and is characterized by atypical verbal/nonverbal communication, restricted interests that can be accompanied by repetitive behavior, and ...
George D. Dalton, Stephen K. Siecinski, Viktoriya D. Nikolova, Gary P. Cofer, Kathryn J. Hornburg, Yi Qi, G. Allan Johnson, Yong-Hui Jiang, Sheryl S. Moy, Simon G. Gregory   +9 more
doaj   +4 more sources

Environmental Enrichment Attenuates Repetitive Behavior and Alters the Functional Connectivity of Pain and Sensory Pathways in C58 Mice [PDF]

Cells
Restricted repetitive behaviors (RRB) encompass a variety of inflexible behaviors, which are diagnostic for autism spectrum disorder (ASD). Despite being requisite diagnostic criteria, the neurocircuitry of these behaviors remains poorly understood ...
Anna L. Farmer, Marcelo Febo, Bradley J. Wilkes, Mark H. Lewis   +3 more
doaj   +3 more sources

Theoretical prediction and experimental verification of protein-coding genes in plant pathogen genome Agrobacterium tumefaciens strain C58. [PDF]

PLoS ONE, 2012
Agrobacterium tumefaciens strain C58 is a Gram-negative soil bacterium capable of inducing tumors (crown galls) on many dicotyledonous plants. The genome of A. tumefaciens strain C58 was re-annotated based on the Z-curve method.
Qian Wang, Yang Lei, Xiwen Xu, Gejiao Wang, Ling-Ling Chen   +4 more
doaj   +3 more sources

Injection but not ingestion of a mixed virus suspension in Queensland fruit fly (Bactrocera tryoni) shifts persistent covert infection to acute pathology. [PDF]

Pest Manag Sci
Covert and persistent infections with multiple insect‐specific viruses are common in pest fruit flies and may affect pest management strategies. Our study investigated the host effects and viral loads of cripavirus and iflavirus as persistent infections in Queensland fruit fly, and after injection and ingestion of a mixed virus suspension containing ...
Sharpe SR, Morrow JL, Tilden G, Katlav A, Riegler M.   +4 more
europepmc   +2 more sources

Reversal learning in C58 mice: Modeling higher order repetitive behavior [PDF]

Behavioural Brain Research, 2017
Restricted, repetitive behaviors are diagnostic for autism and prevalent in other neurodevelopmental disorders. These behaviors cluster as repetitive sensory-motor behaviors and behaviors reflecting resistance to change. The C58 mouse strain is a promising model for these behaviors as it emits high rates of aberrant repetitive sensory-motor behaviors ...
Department of Psychiatry, University of Florida, McKnight Brain Institute Newell Drive, L4-100, Gainesville, FL 32611, USA ( host institution ), Whitehouse, Cristina M. ( UF author ), Curry-Pochy, Lisa S. ( UF author ), Shafer, Robin ( UF author ), Rudy, Joseph ( UF author ), Lewis, Mark H. ( UF author )   +5 more
openaire   +5 more sources

Environmental enrichment reduces restricted repetitive behavior by altering gray matter microstructure. [PDF]

PLoS ONE
Restricted, repetitive behaviors are common symptoms in neurodevelopmental disorders including autism spectrum disorder. Despite being associated with poor developmental outcomes, repetitive behaviors remain poorly understood and have limited treatment ...
Anna L Farmer, Marcelo Febo, Bradley J Wilkes, Mark H Lewis   +3 more
doaj   +2 more sources

Single-nucleotide polymorphism analysis accurately predicts multiple impairments in hippocampal activity and memory performance in a murine model of idiopathic autism [PDF]

Scientific Reports
Autism spectrum disorder (ASD) comprises alterations in brain anatomy and physiology that ultimately affect information processing and behavior. In most cases, autism is considered idiopathic, involving alterations in numerous genes whose functions are ...
Isabel Barón-Mendoza, Luis A. Márquez, Aliesha González-Arenas, Jessica Guzmán-Condado, Vladimir A. Martínez-Rojas, Johaly Anguiano-Buenfil, Montserrat Mejía-Hernández, Jorge Luis Almazán, Leonor Pérez-Martínez, Gustavo Pedraza-Alva, Emilio J. Galván, Angélica Zepeda   +11 more
doaj   +2 more sources

Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion [PDF]

mBio
Multipartite bacterial genome organization can confer advantages, including coordinated gene regulation and faster genome replication, but is challenging to maintain.
Ram Sanath-Kumar, Arafat Rahman, Zhongqing Ren, Ian P. Reynolds, Lauren Augusta, Clay Fuqua, Alexandra J. Weisberg, Xindan Wang   +7 more
doaj   +2 more sources

Co-transformation using T-DNA genes from Agrobacterium strain 82.139 enhances regeneration of transgenic shoots in Populus. [PDF]

Plant Biotechnol J
Summary Barriers to transformation and regeneration continue to hamper the application of recombinant DNA‐based biotechnologies in most crops, including for gene editing. To tackle this problem, there has been increasing interest in morphogenic regulator genes, which aid in regeneration and are often plant developmental master regulator genes.
Goralogia GS, Ma C, Taylor DS, Lawrence A, Conrad V, Peremyslova E, Strauss SH.   +6 more
europepmc   +2 more sources

C58 on Au(111): A scanning tunneling microscopy study [PDF]

The Journal of Chemical Physics, 2013
C58 fullerenes were adsorbed onto room temperature Au(111) surface by low-energy (∼6 eV) cluster ion beam deposition under ultrahigh vacuum conditions. The topographic and electronic properties of the deposits were monitored by means of scanning tunnelling microscopy (STM at 4.2 K).
Bajales, Noelia, Schmaus, Stefan, Miyamashi, Toshio, Wulfhekel, Wulf, Wilhelm, Jan, Walz, Michael, Stendel, Melanie, Bagrets, Alexei, Evers, Ferdinand, Ulas, Seyithan, Kern, Bastian, Böttcher, Artur, Kappes, Manfred M.   +12 more
openaire   +6 more sources