Results 61 to 70 of about 4,504 (203)
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
The performance of firms involved in projects from 2 UK research councils was investigated; firms in Innovate UK projects receive co-funding while firms in Arts & Humanities Research Council (AHRC) projects do not.
Charles Mondal, Robert B. Mellor
doaj +1 more source
During gastrulation of the zebrafish embryo, the cap of blastoderm cells organizes into the axial body plan of the embryo with left–right symmetry and head–tail, dorsal–ventral polarities.
Dipanjan Bhattacharya +4 more
doaj +1 more source
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang +9 more
wiley +1 more source
ABSTRACT The Neolamarckia (Rubiaceae) genus is composed of only two species: N. cadamba and N. macrophylla. Both species are fast‐growing plants with significant industrial and medicinal values. Here, we provided a high‐quality chromosome‐level assembly of the N. macrophylla genome for the first time.
Chao Wu +10 more
wiley +1 more source
Abstrak – Line balancing adalah suatu usaha mengatur lintasan produksi dengan tujuan merencanakan keseimbangan lintasan stasiun kerja (work station) pada tingkat shop floor, guna memperoleh tingkat efisiensi kerja yang tinggi. Proses pembuatan T-Shirt di
Dini Yulianti
doaj +1 more source
Japanese Women's Attitudes Toward Learning Languages Other Than English in the Era of Global English
ABSTRACT This study on female Japanese learners of the Korean language is situated in the centuries‐long anti‐Korean sentiments in Japan, the global popularity of the Korean Wave, particularly among women, and the essentialized image of socially marginalized young Japanese women who study English with romantic desires for Western men.
Yoko Kobayashi
wiley +1 more source
Developmental Toxicity Of Olaparib On Craniofacial Cartilage In Zebrafish
Aim or purpose: Anticancer drugs, classified as emerging contaminants, pose environmental risks due to improper disposal. Olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor widely used in oncology and autoimmune diseases.
Min Huang, Lan Liao, Xianhua Zhang
doaj +1 more source
Nitidine synergises with osimertinib in EGFR‐mutant NSCLC. Nitidine and osimertinib converge on HIF‐1α/FUNDC1‐mediated mitophagy. ABCB6 is required for the nitidine‐associated HIF‐1α/FUNDC1 response. Adaptive FUNDC1 downregulation sensitises osimertinib‐resistant cells to nitidine monotherapy.
Fan Xu +9 more
wiley +1 more source
ANALISIS DAN PERANCANGAN SISTEM INFORMASI PEMESANAN BAHAN BAKU KAOS PADA PT. CALADI LIMA SEMBILAN (C59) [PDF]
ANALISIS DAN PERANCANGAN SISTEM INFORMASI PEMESANAN BAHAN BAKU KAOS PADA PT. CALADI LIMA SEMBILAN (C59) - Material Requirement Planning(MRP),Lot for lot, Part-period, SilverMeal, Wagner Whitin, Sistem Informasi kebutuhan bahan ...
ANINDYAGUNA, NARHA
core

