Results 21 to 30 of about 5,460 (176)
C677T polymorphism increases the risk of early spontaneous abortion [PDF]
Journal of Assisted Reproduction and Genetics, 2019 To investigate the relationship of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in male population having spouses with early spontaneous abortion.A total of 345 males whose spouses had at least one early spontaneous abortion were included in the study group, and 145 males who planned to have a second child were included in the ...
Yongjie Liu, Fan Zhang, Liang Dai
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MTHFR C677T and A1298C Gene Polymorphisms in Human Kidney Cancer Tissues
İstanbul Medical Journal, 2019 Introduction:The potential effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) on DNA methylation, DNA repair and DNA synthesis has made MTHFR a cancer-inducing gene.
Halime Hanım Pençe +4 more
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The C677T Methylenetetrahydrofolate Reductase Gene Mutation in Hemodialysis Patients [PDF]
Journal of the American Society of Nephrology, 2000 Abstract. Hyperhomocysteinemia, which results from renal impairment, may promote arteriosclerosis and glomerulosclerosis. The combined effect of renal failure and a common mutation (C677T) in the methylenetetrahydrofolate reductase gene that leads to serum homocysteine elevations in ...
Hideki, Kimura +3 more
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Association of MTHFR gene C677T polymorphism with pregnancy outcome.
European review for medical and pharmacological sciences, 2023 The two objectives of the present study were to analyze the correlation between pregnancy outcomes and methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism, and to provide evidence for clinical improvement of adverse pregnancy outcomes.1,995 cases of pregnant women were selected as objects of the study, and underwent MTHFR gene C677T ...
Huang, L.-L. +7 more
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Association of MTHFR C677T polymorphism with male infertile in Xiamen area [PDF]
, 2017 目的探讨亚甲基四氢叶酸还原酶（MTHFR）C677T基因多态性与男性不育的相关性。方法选取少、弱精症患者66例和无精症患者74例为实验组,精液正常且有正常孕育史的男性96例为对照组,分析MTHFR C677T基因多态性在三组中分布的差异。结果与对照组相比,少、弱精组中MTHFR C677T各基因型的频率差异没有显著性意义（P〉0.05）;与对照组相比,无精组中MTHFR C677T各基因型的频率差异没有显著性意义（P〉0.05）。结论在少、弱精症患者、无精症患者和健康人中,基因多态性分布无显著差异 ...
谭振军, 王厚照, 马芳芳
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Table2_Regional distribution of the MTHFR C677T polymorphism in Chinese females.docx
, 2023 Objective: For analyzing the distribution characteristics of MTHFR C677T polymorphism in Chinese females in order to provide information for reducing birth defects and formulating public health policies to prevent congenital malformations.Methods ...
Hua Lin (505752) +5 more
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Role of MTHFRC677Tpolymorphism in ischemic stroke [PDF]
Neurology India, 2006 Homozygosity for MTHFR C677T polymorphism can lead to significantly high homocysteine levels and hyperhomocysteinemia is an important risk factor for thrombotic events.The aim was to determine role of MTHFR C677T polymorphism in North Indians with ischemic stroke.In a prospective study, the subjects of stroke were recruited from the neurology clinic of
Inusha Panigrahi +5 more
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Methylene tetrahydrofolate reductase gene mutation in sickle cell anaemia patients in Lagos, Nigeria
The Pan African Medical Journal, 2019 INTRODUCTION: The significant causes of mortality among individuals with sickle cell anaemia (SCA) such as acute chest syndrome and cerebrovascular disease are related to vascular occlusion.
Oluwaseun Olabisi Adelekan +8 more
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Frontiers in Neurology, 2019 Vitamin B12 deficiency is regarded as the prevailing cause of subacute combined degeneration of the spinal cord (SCD). Nevertheless, the genetic predisposition to SCD remains unclear.
Xin Zhang +7 more
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Annals of Saudi Medicine, 2021 BACKGROUND: Methylenetetrahydrofolate reductase, the encoded by the MTHFR gene, plays a crucial role in converting the amino acid homocysteine to methionine.
Amina M. Bagher +5 more
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